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Literature DB >> 18361352

Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons.

Kenneth J Oh¹, Kevin J Cash, Arica A Lubin, Kevin W Plaxco.

Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide-peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

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Year: 2007 PMID： 18361352 PMCID： PMC2692638 DOI： 10.1039/b709776j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

25 in total

1. Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.

Authors: A Y Ting; K H Kain; R L Klemke; R Y Tsien
Journal: Proc Natl Acad Sci U S A Date: 2001-12-18 Impact factor: 11.205

2. Collection of trace amounts of DNA/mRNA molecules using genomagnetic nanocapturers.

Authors: Xiaojun Zhao; Rovelyn Tapec-Dytioco; Kemin Wang; Weihong Tan
Journal: Anal Chem Date: 2003-07-15 Impact factor: 6.986

3. Engineering a signal transduction mechanism for protein-based biosensors.

Authors: Jonathan E Kohn; Kevin W Plaxco
Journal: Proc Natl Acad Sci U S A Date: 2005-07-26 Impact factor: 11.205

4. An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids.

Authors: Brian R Baker; Rebecca Y Lai; McCall S Wood; Elaine H Doctor; Alan J Heeger; Kevin W Plaxco
Journal: J Am Chem Soc Date: 2006-03-15 Impact factor: 15.419

5. Dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding.

Authors: Florian Krieger; Beat Fierz; Oliver Bieri; Mario Drewello; Thomas Kiefhaber
Journal: J Mol Biol Date: 2003-09-05 Impact factor: 5.469

6. Molecular beacons: probes that fluoresce upon hybridization.

Authors: S Tyagi; F R Kramer
Journal: Nat Biotechnol Date: 1996-03 Impact factor: 54.908

7. Evaluation of the affinity measurement of anti-HIV-1 p17 monoclonal antibody by BIAcore.

Authors: A Ota; S Ueda
Journal: Hybridoma Date: 1998-10

8. Excimer-based peptide beacons: a convenient experimental approach for monitoring polypeptide-protein and polypeptide-oligonucleotide interactions.

Authors: Kenneth J Oh; Kevin J Cash; Kevin W Plaxco
Journal: J Am Chem Soc Date: 2006-11-01 Impact factor: 15.419

Review 6. Fluorogenic PNA probes.

Authors: Tirayut Vilaivan
Journal: Beilstein J Org Chem Date: 2018-01-29 Impact factor: 2.883

7. Coiled-Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection.

Authors: Carolin Mueller; Tom N Grossmann
Journal: Angew Chem Int Ed Engl Date: 2018-11-28 Impact factor: 15.336

7 in total

Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons.

1. Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.

2. Collection of trace amounts of DNA/mRNA molecules using genomagnetic nanocapturers.

3. Engineering a signal transduction mechanism for protein-based biosensors.

4. An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids.

5. Dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding.

6. Molecular beacons: probes that fluoresce upon hybridization.

7. Evaluation of the affinity measurement of anti-HIV-1 p17 monoclonal antibody by BIAcore.

8. Excimer-based peptide beacons: a convenient experimental approach for monitoring polypeptide-protein and polypeptide-oligonucleotide interactions.

Review 9. Making antibodies by phage display technology.

10. Synthetic DNA aptamers to detect protein molecular variants in a high-throughput fluorescence quenching assay.

Review 1. Converting a protein into a switch for biosensing and functional regulation.

2. Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures.

3. A Modular, DNA-Based Beacon for Single-Step Fluorescence Detection of Antibodies and Other Proteins.

4. Beyond molecular beacons: optical sensors based on the binding-induced folding of proteins and polypeptides.

Review 5. Nucleic Acid Templated Reactions for Chemical Biology.

Review 6. Fluorogenic PNA probes.

7. Coiled-Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection.