Literature DB >> 1835236

Back pain: a study of twins.

B Bengtsson1, J Thorson.   

Abstract

To evaluate the relationship between genetic factors and back pain, 5029 MZ and 7876 DZ twin pairs were investigated by a questionnaire. The data were analyzed with regard to physical symptoms, eg, back pain, and certain work conditions. Pain was reported by about 17% of the male and 13% of the female twins in the material. The occurrence of back pain was strongly associated with work load, especially among the male twins. Twin concordance regarding back pain was considerably higher in MZ than in DZ twins. Of four groups who were studied, statistically significant differences between the two twin categories were observed in three cases. This result supports the assumption that a relationship exists between genetic factors and the occurrence of back pain. Official registrations for sick-leave pay in a sample of 247 twins confirmed the interview information on back pain. Just a few cases were wrongly classified, ie, they were sick-listed because of back pain but had stated no back pain in the questionnaire.

Entities:  

Mesh：

Year:  1991        PMID： 1835236     DOI： 10.1017/s0001566000006760

Source DB:  PubMed          Journal:  Acta Genet Med Gemellol (Roma)        ISSN： 0001-5660


  9 in total

1.  Ambiguous relation between physical workload and low back pain: a twin control study.

Authors:  J Hartvigsen; K O Kyvik; C Leboeuf-Yde; S Lings; L Bakketeig
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2.  Adolescent flexibility, endurance strength, and physical activity as predictors of adult tension neck, low back pain, and knee injury: a 25 year follow up study.

Authors:  L O Mikkelsson; H Nupponen; J Kaprio; H Kautiainen; M Mikkelsson; U M Kujala
Journal:  Br J Sports Med       Date:  2006-02       Impact factor: 13.800

Review 3.  Bone health and back pain: what do we know and where should we go?

Authors:  A M Briggs; L M Straker; J D Wark
Journal:  Osteoporos Int       Date:  2008-08-21       Impact factor: 4.507

Review 4.  Twin studies for the prognosis, prevention and treatment of musculoskeletal conditions.

Authors:  Lucas Calais-Ferreira; Vinicius C Oliveira; Jeffrey M Craig; Louisa B Flander; John L Hopper; Luci F Teixeira-Salmela; Paulo H Ferreira
Journal:  Braz J Phys Ther       Date:  2017-12-27       Impact factor: 3.377

Review 5.  The genetic mediation of individual differences in sensitivity to pain and its inhibition.

Authors:  J S Mogil
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

6.  Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene.

Authors:  Sophie C Warner; Joyce Bj van Meurs; Dieuwke Schiphof; Sita M Bierma-Zeinstra; Albert Hofman; Andre G Uitterlinden; Helen Richardson; Wendy Jenkins; Michael Doherty; Ana M Valdes
Journal:  Eur J Hum Genet       Date:  2017-01-04       Impact factor: 4.246

7.  Genetic and environmental influences on non-specific low back pain in children: a twin study.

Authors:  Ashraf El-Metwally; Marja Mikkelsson; Minna Ståhl; Gary J Macfarlane; Gareth T Jones; Lea Pulkkinen; Richard J Rose; Jaakko Kaprio
Journal:  Eur Spine J       Date:  2008-01-18       Impact factor: 3.134

8.  The human μ-opioid receptor gene polymorphism (A118G) is associated with head pain severity in a clinical cohort of female migraine with aura patients.

Authors:  S Menon; R A Lea; B Roy; M Hanna; S Wee; L M Haupt; L R Griffiths
Journal:  J Headache Pain       Date:  2012-06-30       Impact factor: 7.277

9.  Low back pain in military recruits in relation to social background and previous low back pain. A cross-sectional and prospective observational survey.

Authors:  Lise Hestbaek; Kristian Larsen; Flemming Weidick; Charlotte Leboeuf-Yde
Journal:  BMC Musculoskelet Disord       Date:  2005-05-26       Impact factor: 2.362
  9 in total

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