Literature DB >> 18337534

Patients' adherence to osteoporosis therapy: exploring the perceptions of postmenopausal women.

Elaine Lau1, Alexandra Papaioannou, Lisa Dolovich, Jonathan Adachi, Anna M Sawka, Sheri Burns, Kalpana Nair, Anjali Pathak.   

Abstract

OBJECTIVE: To explore the experiences and perceptions of postmenopausal women regarding strategies to improve adherence to osteoporosis therapy.
DESIGN: Qualitative, mixed phenomenologic study using focus groups.
SETTING: Family physicians' and specialists' practices and community pharmacies in Hamilton, Ont. PARTICIPANTS: A total of 37 postmenopausal women currently taking at least 1 prescription or over-the-counter medication for osteoporosis.
METHOD: Focus groups were conducted using a semistructured interview guide consisting of 10 open-ended questions about patients' perceptions of their osteoporosis medications, their reasons for adherence and non-adherence to therapy, and the effectiveness of strategies they had tried to improve adherence. At least 2 research team members analyzed the data to find primary themes. MAIN
FINDINGS: Analysis of data from the 7 focus groups found 6 main factors that influenced adherence to medications: belief in the importance of taking medications for osteoporosis, medication-specific factors, beliefs regarding medications and health, relationships with health care providers, information exchange, and strategies to improve adherence. Strategies that facilitated adherence to medications included having a system for taking medications, using cues or reminders, being well informed about the reasons for taking medications, and having regular follow-up by health care providers for support and monitoring after having been prescribed medications.
CONCLUSION: Results of this study provide a better understanding of how patients' perceptions and experiences affect their adherence to osteoporosis medications. Because each patient's reasons for non-adherence might be different, depending on individual beliefs or circumstances, strategies to improve adherence to medications should be individualized accordingly.

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Year:  2008        PMID: 18337534      PMCID: PMC2278357     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  32 in total

1.  Effect of dosing frequency on bisphosphonate medication adherence in a large longitudinal cohort of women.

Authors:  Robert R Recker; Rich Gallagher; Paul E MacCosbe
Journal:  Mayo Clin Proc       Date:  2005-07       Impact factor: 7.616

2.  Assessment of compliance with osteoporosis treatment and its consequences in a managed care population.

Authors:  Krista F Huybrechts; Khajak J Ishak; J Jaime Caro
Journal:  Bone       Date:  2005-12-05       Impact factor: 4.398

3.  Compliance with osteoporosis medications.

Authors:  Daniel H Solomon; Jerry Avorn; Jeffrey N Katz; Joel S Finkelstein; Marilyn Arnold; Jennifer M Polinski; M Alan Brookhart
Journal:  Arch Intern Med       Date:  2005-11-14

4.  Osteoporosis management: physicians' recommendations and womens' compliance following osteoporosis testing.

Authors:  R P Cole; S Palushock; A Haboubi
Journal:  Women Health       Date:  1999

5.  Compliance and persistence with bisphosphonate dosing regimens among women with postmenopausal osteoporosis.

Authors:  Joyce A Cramer; Mayur M Amonkar; Ansgar Hebborn; Roy Altman
Journal:  Curr Med Res Opin       Date:  2005-09       Impact factor: 2.580

6.  Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases.

Authors:  Ethel S Siris; Steven T Harris; Clifford J Rosen; Charles E Barr; James N Arvesen; Thomas A Abbott; Stuart Silverman
Journal:  Mayo Clin Proc       Date:  2006-08       Impact factor: 7.616

7.  Determinants of persistence with bisphosphonates: a study in women with postmenopausal osteoporosis.

Authors:  Fernie J A Penning-van Beest; Wim G Goettsch; Joëlle A Erkens; Ron M C Herings
Journal:  Clin Ther       Date:  2006-02       Impact factor: 3.393

8.  Compliance with drug therapy for postmenopausal osteoporosis.

Authors:  D Weycker; D Macarios; J Edelsberg; G Oster
Journal:  Osteoporos Int       Date:  2006-07-22       Impact factor: 4.507

Review 9.  Interventions to enhance medication adherence.

Authors:  R B Haynes; X Yao; A Degani; S Kripalani; A Garg; H P McDonald
Journal:  Cochrane Database Syst Rev       Date:  2005-10-19

10.  The impact of compliance with osteoporosis therapy on fracture rates in actual practice.

Authors:  J Jaime Caro; Khajak J Ishak; Krista F Huybrechts; Gabriel Raggio; Christel Naujoks
Journal:  Osteoporos Int       Date:  2004-05-27       Impact factor: 4.507

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  23 in total

Review 1.  Measuring and improving adherence to osteoporosis pharmacotherapy.

Authors:  Suzanne M Cadarette; Andrea M Burden
Journal:  Curr Opin Rheumatol       Date:  2010-07       Impact factor: 5.006

2.  Formulating medication adherence strategies using the PASSAction framework.

Authors:  Vivian K T Lee
Journal:  Can Pharm J (Ott)       Date:  2013-01

3.  Osteoporosis pharmacotherapy following bone densitometry: importance of patient beliefs and understanding of DXA results.

Authors:  D Brask-Lindemann; S M Cadarette; P Eskildsen; B Abrahamsen
Journal:  Osteoporos Int       Date:  2010-08-04       Impact factor: 4.507

Review 4.  A systematic review of factors affecting medication adherence among patients with osteoporosis.

Authors:  C T Yeam; S Chia; H C C Tan; Y H Kwan; W Fong; J J B Seng
Journal:  Osteoporos Int       Date:  2018-11-12       Impact factor: 4.507

5.  Patient-reported reasons for nonadherence to recommended osteoporosis pharmacotherapy.

Authors:  Sylvie F Hall; Stephanie W Edmonds; Yiyue Lou; Peter Cram; Douglas W Roblin; Kenneth G Saag; Nicole C Wright; Michael P Jones; Fredric D Wolinsky
Journal:  J Am Pharm Assoc (2003)       Date:  2017-06-08

6.  Individual patients hold different beliefs to prescription medications to which they persist vs nonpersist and persist vs nonfulfill.

Authors:  Colleen A McHorney; Abhijit S Gadkari
Journal:  Patient Prefer Adherence       Date:  2010-07-21       Impact factor: 2.711

7.  Determinant factors of osteoporosis patients' reported therapeutic adherence to calcium and/or vitamin D supplements: a cross-sectional, observational study of postmenopausal women.

Authors:  José Sanfelix-Genovés; Vicente F Gil-Guillén; Domingo Orozco-Beltran; Vicente Giner-Ruiz; Salvador Pertusa-Martínez; Begoña Reig-Moya; Concepción Carratalá
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

8.  Non-adherence to anti-osteoporotic medications in Taiwan: physician specialty makes a difference.

Authors:  Shan-Fu Yu; Tsong-Shing Yang; Wen-Chan Chiu; Chung-Yuan Hsu; Ching-Lan Chou; Yu-Jih Su; Han-Ming Lai; Ying-Chou Chen; Chung-Jen Chen; Tien-Tsai Cheng
Journal:  J Bone Miner Metab       Date:  2013-02-02       Impact factor: 2.626

9.  Patient-Provider Communication With Older Adults About Sleep Apnea Diagnosis and Treatment.

Authors:  Constance H Fung; Cathy Alessi; Cindy Truong; Karen Josephson; Ron D Hays; Nananda Col; Emily S Patterson; Jennifer L Martin
Journal:  Behav Sleep Med       Date:  2016-05-04       Impact factor: 2.964

Review 10.  Adherence to osteoporosis treatments: room for improvement.

Authors:  Amy H Warriner; Jeffrey R Curtis
Journal:  Curr Opin Rheumatol       Date:  2009-07       Impact factor: 5.006

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