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Literature DB >> 18336438

Microarray technology applied to the complex disorder of preeclampsia.

Sandra A Founds¹, Janice S Dorman, Yvette P Conley.

Abstract

Preeclampsia is a life-threatening perinatal complication with unknown etiology. Microarray technology has characterized global gene expression in complex disorders such as preeclampsia. Nursing research and future practice may incorporate findings from microarray analyses to identify susceptibility to and prevent disease, to diagnose early, and to design and monitor personalized therapies. This overview of microarray technology, with emphasis on how it can inform genomics of preeclampsia, may provide concepts to improve future maternal-neonatal nursing care.

Mesh：

Year: 2008 PMID： 18336438 DOI： 10.1111/j.1552-6909.2008.00232.x

Source DB: PubMed Journal: J Obstet Gynecol Neonatal Nurs ISSN： 0090-0311

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Cited

12 in total

1. Gene expression in first trimester preeclampsia placenta.

Authors: Sandra A Founds; Lauren A Terhorst; Kirk P Conrad; W Allen Hogge; Arun Jeyabalan; Yvette P Conley
Journal: Biol Res Nurs Date: 2010-11-01 Impact factor: 2.522

2. Gene expression profiling of placentae from women with early- and late-onset pre-eclampsia: down-regulation of the angiogenesis-related genes ACVRL1 and EGFL7 in early-onset disease.

Authors: K Junus; M Centlow; A-K Wikström; I Larsson; S R Hansson; M Olovsson
Journal: Mol Hum Reprod Date: 2011-10-19 Impact factor: 4.025

10. The role of angiogenic, anti-angiogenic and vasoactive factors in pre-eclamptic African women: early- versus late-onset pre-eclampsia.

Authors: Lucinda Govender; Irene Mackraj; Prem Gathiram; Jack Moodley
Journal: Cardiovasc J Afr Date: 2012-04 Impact factor: 1.167

Microarray technology applied to the complex disorder of preeclampsia.

1. Gene expression in first trimester preeclampsia placenta.

2. Gene expression profiling of placentae from women with early- and late-onset pre-eclampsia: down-regulation of the angiogenesis-related genes ACVRL1 and EGFL7 in early-onset disease.

3. Gene expression of four targets in situ of the first trimester maternal-fetoplacental interface.

4. Associating Symptom Phenotype and Genotype in Preeclampsia.

5. A transcriptional profile of the decidua in preeclampsia.

6. Gene expression profiling of placentas affected by pre-eclampsia.

7. Variations in discovery-based preeclampsia candidate genes.

8. FOXO1 expression in villous trophoblast of preeclampsia and fetal growth restriction placentas.

9. Altered global gene expression in first trimester placentas of women destined to develop preeclampsia.

10. The role of angiogenic, anti-angiogenic and vasoactive factors in pre-eclamptic African women: early- versus late-onset pre-eclampsia.