Literature DB >> 18330989

In vivo and in vitro production options for fungal secondary metabolites.

Patrick Schneider1, Mathias Misiek, Dirk Hoffmeister.   

Abstract

Microbial natural products, among them a vast diversity of fungal origin, represent a major source for new drug candidates. Focusing on fungal metabolites, our review covers recent advances in the field of biotransformation, heterologous expression, in vivo production approaches, genomics, and the metabolism of unexplored fungal groups as options to generate and identify new compounds or optimize known ones.

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Year:  2008        PMID： 18330989     DOI： 10.1021/mp7001544

Source DB:  PubMed          Journal:  Mol Pharm        ISSN： 1543-8384            Impact factor:   4.939


  22 in total

Review 1.  Metabolic engineering for the production of natural products.

Authors:  Lauren B Pickens; Yi Tang; Yit-Heng Chooi
Journal:  Annu Rev Chem Biomol Eng       Date:  2011       Impact factor: 11.059

Review 2.  Fungal Endophytes: A Potential Source of Antibacterial Compounds.

Authors:  Sunil K Deshmukh; Laurent Dufossé; Hemraj Chhipa; Sanjai Saxena; Girish B Mahajan; Manish Kumar Gupta
Journal:  J Fungi (Basel)       Date:  2022-02-08

Review 3.  Unlocking fungal cryptic natural products.

Authors:  Yi-Ming Chiang; Kuan-Han Lee; James F Sanchez; Nancy P Keller; Clay C C Wang
Journal:  Nat Prod Commun       Date:  2009-11       Impact factor: 0.986

4.  Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus.

Authors:  Ry R Forseth; Saori Amaike; Daniel Schwenk; Katharyn J Affeldt; Dirk Hoffmeister; Frank C Schroeder; Nancy P Keller
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-20       Impact factor: 15.336

5.  Activation of the dormant secondary metabolite production by introducing gentamicin-resistance in a marine-derived Penicillium purpurogenum G59.

Authors:  Yun-Jing Chai; Cheng-Bin Cui; Chang-Wei Li; Chang-Jing Wu; Cong-Kui Tian; Wei Hua
Journal:  Mar Drugs       Date:  2012-03-02       Impact factor: 6.085

6.  Enhancement of Palmarumycins C(12) and C(13) production in liquid culture of endophytic fungus Berkleasmium sp. Dzf12 after treatments with metal ions.

Authors:  Yan Mou; Haiyu Luo; Ziling Mao; Tijiang Shan; Weibo Sun; Kaiyi Zhou; Ligang Zhou
Journal:  Int J Mol Sci       Date:  2013-01-07       Impact factor: 5.923

7.  Three new and eleven known unusual C25 steroids: activated production of silent metabolites in a marine-derived fungus by chemical mutagenesis strategy using diethyl sulphate.

Authors:  Ming-Wen Xia; Cheng-Bin Cui; Chang-Wei Li; Chang-Jing Wu
Journal:  Mar Drugs       Date:  2014-03-13       Impact factor: 5.118

8.  A Novel Metabolite from Aspergillus ochraceus JGI 25 Showing Cytotoxicity to Hela Cells.

Authors:  Varalakshmi K Nadumane; Prerana Venkat; Anamika Pal; H Dharod; Megha Shukla; K Prashanthi
Journal:  Indian J Pharm Sci       Date:  2013-09       Impact factor: 0.975

Review 9.  Small-molecule elicitation of microbial secondary metabolites.

Authors:  Robin K Pettit
Journal:  Microb Biotechnol       Date:  2010-07-26       Impact factor: 5.813

10.  Chemical characterization of bioactive compounds from the endophytic fungus Diaporthe helianthi isolated from Luehea divaricata.

Authors:  Vânia Specian; Maria Helena Sarragiotto; João Alencar Pamphile; Edmar Clemente
Journal:  Braz J Microbiol       Date:  2012-06-01       Impact factor: 2.476
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