Literature DB >> 18317242

Children of persons with Alzheimer disease: what does the future hold?

Lissy Jarvik1, Asenath LaRue, Deborah Blacker, Margaret Gatz, Claudia Kawas, John J McArdle, John C Morris, James A Mortimer, John M Ringman, Linda Ercoli, Nelson Freimer, Izabella Gokhman, Jennifer J Manly, Brenda L Plassman, Natalie Rasgon, Jeffrey Scott Roberts, Trey Sunderland, Gary E Swan, Phillip A Wolf, Alan B Zonderman.   

Abstract

Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD. Many of them, throughout their adult lives, seek input on how to reduce their chances of one day suffering their parent's fate. We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring.

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Year:  2008        PMID: 18317242      PMCID: PMC3377487          DOI: 10.1097/WAD.0b013e31816653ac

Source DB:  PubMed          Journal:  Alzheimer Dis Assoc Disord        ISSN: 0893-0341            Impact factor:   2.703


  189 in total

1.  Childhood mental ability and dementia.

Authors:  L J Whalley; J M Starr; R Athawes; D Hunter; A Pattie; I J Deary
Journal:  Neurology       Date:  2000-11-28       Impact factor: 9.910

2.  Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease.

Authors:  Trey Sunderland; Gary Linker; Nadeem Mirza; Karen T Putnam; David L Friedman; Lida H Kimmel; Judy Bergeson; Guy J Manetti; Matthew Zimmermann; Brian Tang; John J Bartko; Robert M Cohen
Journal:  JAMA       Date:  2003 Apr 23-30       Impact factor: 56.272

3.  Dietary fats and the risk of incident Alzheimer disease.

Authors:  Martha Clare Morris; Denis A Evans; Julia L Bienias; Christine C Tangney; David A Bennett; Neelum Aggarwal; Julie Schneider; Robert S Wilson
Journal:  Arch Neurol       Date:  2003-02

4.  Apolipoprotein E and cognitive performance: a meta-analysis.

Authors:  Brent J Small; Christopher B Rosnick; Laura Fratiglioni; Lars Bäckman
Journal:  Psychol Aging       Date:  2004-12

5.  Context-specific memory and apolipoprotein E (ApoE) epsilon 4: cognitive evidence from the NIMH prospective study of risk for Alzheimer's disease.

Authors:  James A Levy; Judy Bergeson; Karen Putnam; Virginia Rosen; Robert Cohen; Francois Lalonde; Nadeem Mirza; Gary Linker; Trey Sunderland
Journal:  J Int Neuropsychol Soc       Date:  2004-05       Impact factor: 2.892

6.  Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study.

Authors:  Peter P Zandi; James C Anthony; Ara S Khachaturian; Stephanie V Stone; Deborah Gustafson; JoAnn T Tschanz; Maria C Norton; Kathleen A Welsh-Bohmer; John C S Breitner
Journal:  Arch Neurol       Date:  2004-01

7.  DNA polymorphisms of apolipoprotein B and angiotensin I-converting enzyme genes and relationships with lipid levels in Italian patients with vascular dementia or Alzheimer's disease.

Authors:  R Scacchi; L De Bernardini; E Mantuano; T Vilardo; L M Donini; M Ruggeri; A T Gemma; R Pascone; R M Corbo
Journal:  Dement Geriatr Cogn Disord       Date:  1998 Jul-Aug       Impact factor: 2.959

8.  Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial.

Authors:  C G Lyketsos; J C S Breitner; R C Green; B K Martin; C Meinert; S Piantadosi; M Sabbagh
Journal:  Neurology       Date:  2007-04-25       Impact factor: 9.910

9.  Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOE e4 allele.

Authors:  R J Caselli; E M Reiman; D Osborne; J G Hentz; L C Baxter; J L Hernandez; G G Alexander
Journal:  Neurology       Date:  2004-06-08       Impact factor: 9.910

10.  Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.

Authors:  L A Farrer; L A Cupples; J L Haines; B Hyman; W A Kukull; R Mayeux; R H Myers; M A Pericak-Vance; N Risch; C M van Duijn
Journal:  JAMA       Date:  1997 Oct 22-29       Impact factor: 56.272

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  18 in total

Review 1.  Cerebral blood flow measured by arterial spin labeling MRI as a preclinical marker of Alzheimer's disease.

Authors:  Christina E Wierenga; Chelsea C Hays; Zvinka Z Zlatar
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

2.  Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's disease.

Authors:  N Maritza Dowling; Bruce Hermann; Asenath La Rue; Mark A Sager
Journal:  Neuropsychology       Date:  2010-11       Impact factor: 3.295

3.  Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease.

Authors:  Ozioma C Okonkwo; Guofan Xu; Jennifer M Oh; N Maritza Dowling; Cynthia M Carlsson; Catherine L Gallagher; Alex C Birdsill; Matthew Palotti; Whitney Wharton; Bruce P Hermann; Asenath LaRue; Barbara B Bendlin; Howard A Rowley; Sanjay Asthana; Mark A Sager; Sterling C Johnson
Journal:  Cereb Cortex       Date:  2012-12-12       Impact factor: 5.357

Review 4.  The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer's Disease.

Authors:  Chelsea C Hays; Zvinka Z Zlatar; Christina E Wierenga
Journal:  Cell Mol Neurobiol       Date:  2016-02-22       Impact factor: 5.046

5.  Influence of Alzheimer disease family history and genetic risk on cognitive performance in healthy middle-aged and older people.

Authors:  Markus Donix; Linda M Ercoli; Prabha Siddarth; Jesse A Brown; Laurel Martin-Harris; Alison C Burggren; Karen J Miller; Gary W Small; Susan Y Bookheimer
Journal:  Am J Geriatr Psychiatry       Date:  2012-07       Impact factor: 4.105

Review 6.  Early-Onset Alzheimer Disease.

Authors:  Mario F Mendez
Journal:  Neurol Clin       Date:  2017-05       Impact factor: 3.806

7.  A diffusion model analysis of episodic recognition in preclinical individuals with a family history for Alzheimer's disease: The adult children study.

Authors:  Andrew J Aschenbrenner; David A Balota; Brian A Gordon; Roger Ratcliff; John C Morris
Journal:  Neuropsychology       Date:  2016-02       Impact factor: 3.295

8.  Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity.

Authors:  Stella E Panos; Charles H Hinkin; Elyse J Singer; April D Thames; Sapna M Patel; Janet S Sinsheimer; A C Del Re; Benjamin B Gelman; Susan Morgello; David J Moore; Andrew J Levine
Journal:  Neurobehav HIV Med       Date:  2013-06-19

9.  Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.

Authors:  Jacqueline E Maye; Rebecca A Betensky; Christopher M Gidicsin; Joseph Locascio; J Alex Becker; Lesley Pepin; Jeremy Carmasin; Dorene M Rentz; Gad A Marshall; Deborah Blacker; Reisa A Sperling; Keith A Johnson
Journal:  Neurobiol Aging       Date:  2015-12-28       Impact factor: 4.673

10.  Cognitive activities and cognitive performance in middle-aged adults at risk for Alzheimer's disease.

Authors:  Erin Jonaitis; Asenath La Rue; Kimberly D Mueller; Rebecca L Koscik; Bruce Hermann; Mark A Sager
Journal:  Psychol Aging       Date:  2013-12
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