Literature DB >> 28410659

Early-Onset Alzheimer Disease.

Mario F Mendez1.   

Abstract

Early-onset Alzheimer disease (EOAD), with onset in individuals younger than 65 years, although overshadowed by the more common late-onset AD (LOAD), differs significantly from LOAD. EOAD comprises approximately 5% of AD and is associated with delays in diagnosis, aggressive course, and age-related psychosocial needs. One source of confusion is that a substantial percentage of EOAD are phenotypic variants that differ from the usual memory-disordered presentation of typical AD. The management of EOAD is similar to that for LOAD, but special emphasis should be placed on targeting the specific cognitive areas involved and more age-appropriate psychosocial support and education.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Alzheimer disease; Dementia; Early-onset dementia; Logopenic variant primary progressive aphasia; Progressive cortical atrophy; Young-onset dementia

Mesh：

Year:  2017        PMID： 28410659      PMCID： PMC5407192          DOI： 10.1016/j.ncl.2017.01.005

Source DB:  PubMed          Journal:  Neurol Clin        ISSN： 0733-8619            Impact factor:   3.806


  151 in total

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Journal:  Eur J Hum Genet       Date:  2015-08-05       Impact factor: 4.246

2.  Early-onset dementia is associated with higher mortality.

Authors:  Esther L G E Koedam; Yolande A L Pijnenburg; Dorly J H Deeg; Merel M E Baak; Annelies E van der Vlies; Philip Scheltens; Wiesje M van der Flier
Journal:  Dement Geriatr Cogn Disord       Date:  2008-08-04       Impact factor: 2.959

3.  Early onset Alzheimer's disease is associated with a distinct neuropsychological profile.

Authors:  Lieke L Smits; Yolande A L Pijnenburg; Esther L G E Koedam; Annelies E van der Vlies; Ilona E W Reuling; Teddy Koene; Charlotte E Teunissen; Philip Scheltens; Wiesje M van der Flier
Journal:  J Alzheimers Dis       Date:  2012       Impact factor: 4.472

4.  Differences in routine clinical practice between early and late onset Alzheimer's disease: data from the Swedish Dementia Registry (SveDem).

Authors:  Hanna Eriksson; Seyed-Mohammad Fereshtehnejad; Farshad Falahati; Bahman Farahmand; Dorota Religa; Maria Eriksdotter
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

5.  Executive dysfunction in early Alzheimer's disease.

Authors:  G Binetti; E Magni; A Padovani; S F Cappa; A Bianchetti; M Trabucchi
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-01       Impact factor: 10.154

6.  The unique experience of spouses in early-onset dementia.

Authors:  Francine Ducharme; Marie-Jeanne Kergoat; Pascal Antoine; Florence Pasquier; Renée Coulombe
Journal:  Am J Alzheimers Dis Other Demen       Date:  2013-07-02       Impact factor: 2.035

Review 7.  Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: from animal models to human findings.

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Journal:  Prog Neurobiol       Date:  2012-07-10       Impact factor: 11.685

8.  Variability in cognitive presentation of Alzheimer's disease.

Authors:  Cheryl L Stopford; Julie S Snowden; Jennifer C Thompson; David Neary
Journal:  Cortex       Date:  2007-11-17       Impact factor: 4.027

9.  Cognitive phenotypes in Alzheimer's disease and genetic risk.

Authors:  Julie S Snowden; Cheryl L Stopford; Camille L Julien; Jennifer C Thompson; Yvonne Davidson; Linda Gibbons; Antonia Pritchard; Corinne L Lendon; Anna M Richardson; Anoop Varma; David Neary; David Mann
Journal:  Cortex       Date:  2007-10       Impact factor: 4.027

10.  Childhood Learning Disabilities and Atypical Dementia: A Retrospective Chart Review.

Authors:  Alon Seifan; Stephanie Assuras; Edward D Huey; Jesse Mez; Angeliki Tsapanou; Elise Caccappolo
Journal:  PLoS One       Date:  2015-06-24       Impact factor: 3.240
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  56 in total

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Journal:  Ann Transl Med       Date:  2018-05

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3.  Rethinking dementias.

Authors:  E Sinforiani; Matteo Cotta Ramusino; Alfredo Costa
Journal:  Funct Neurol       Date:  2017 Jul/Sep

4.  Prognostic value of Alzheimer's biomarkers in mild cognitive impairment: the effect of age at onset.

Authors:  Daniele Altomare; Clarissa Ferrari; Anna Caroli; Samantha Galluzzi; Annapaola Prestia; Wiesje M van der Flier; Rik Ossenkoppele; Bart Van Berckel; Frederik Barkhof; Charlotte E Teunissen; Anders Wall; Stephen F Carter; Michael Schöll; I L Han Choo; Timo Grimmer; Alberto Redolfi; Agneta Nordberg; Philip Scheltens; Alexander Drzezga; Giovanni B Frisoni
Journal:  J Neurol       Date:  2019-07-02       Impact factor: 4.849

Review 5.  Early-onset Alzheimer Disease and Its Variants.

Authors:  Mario F Mendez
Journal:  Continuum (Minneap Minn)       Date:  2019-02

Review 6.  Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis.

Authors:  Gada Musa; Andrea Slachevsky; Carlos Muñoz-Neira; Carolina Méndez-Orellana; Roque Villagra; Christian González-Billault; Agustín Ibáñez; Michael Hornberger; Patricia Lillo
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7.  18F-THK 5351 and 11C-PiB PET of the Thai normal brain template.

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8.  Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer's disease subgroups.

Authors:  Colin Groot; Michel J Grothe; Shubhabrata Mukherjee; Irina Jelistratova; Iris Jansen; Anna Catharina van Loenhoud; Shannon L Risacher; Andrew J Saykin; Christine L Mac Donald; Jesse Mez; Emily H Trittschuh; Gregor Gryglewski; Rupert Lanzenberger; Yolande A L Pijnenburg; Frederik Barkhof; Philip Scheltens; Wiesje M van der Flier; Paul K Crane; Rik Ossenkoppele
Journal:  Neuroimage Clin       Date:  2021-04-03       Impact factor: 4.881

9.  The predictive value of normal EEGs in dementia due to Alzheimer's disease.

Authors:  Casper T Briels; Cornelis J Stam; Philip Scheltens; Alida A Gouw
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10.  ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration.

Authors:  Katheryn A Q Cousins; David J Irwin; David A Wolk; Edward B Lee; Leslie M J Shaw; John Q Trojanowski; Fulvio Da Re; Garrett S Gibbons; Murray Grossman; Jeffrey S Phillips
Journal:  Brain       Date:  2020-07-01       Impact factor: 13.501
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