| Literature DB >> 18312863 |
Takashi Nagaike1, Tsutomu Suzuki, Takuya Ueda.
Abstract
Polyadenylation in animal mitochondria is very unique. Unlike other systems, polyadenylation is needed to generate UAA stop codons that are not encoded in mitochondrial (mt) DNA. In some cases, polyadenylation is required for the mt tRNA maturation by editing of its 3' termini. Furthermore, recent studies on human mt poly(A) polymerase (PAP) and PNPase provide new insights and questions for the regulatory mechanism and functional role of polyadenylation in human mitochondria.Entities:
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Year: 2008 PMID: 18312863 DOI: 10.1016/j.bbagrm.2008.02.001
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002