| Literature DB >> 18311991 |
Masato Nozawa1, Yuhki Suka, Takashi Hoshi, Toshio Suzuki, Hisahiro Hagiwara.
Abstract
Total synthesis of salvinorin A (1), a neoclerodane diterpenoid having the most potent hallucinogenic activity and a selective kappa-opioid agonist, was completed in 20 steps starting from enantiomerically pure hydroxy-Wieland-Miescher ketone 5.Entities:
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Year: 2008 PMID： 18311991 DOI： 10.1021/ol800101v
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005