| Literature DB >> 18308566 |
David A James1, Keizo Koya, Hao Li, Guiqing Liang, Zhiqiang Xia, Weiwen Ying, Yaming Wu, Lijun Sun.
Abstract
We report herein the SAR studies of a series of indole- and indolizine-glyoxylamides that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine).Entities:
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Year: 2008 PMID： 18308566 DOI： 10.1016/j.bmcl.2008.02.029
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823