Literature DB >> 18292368

Fracture repair: successful advances, persistent problems, and the psychological burden of trauma.

Adam J Starr1.   

Abstract

This article is intended to deliver three messages. First, minimally invasive methods of fracture repair are successful; when coupled with advances in implant design, these techniques yield higher union rates with fewer complications than prior methods of direct open fracture repair. Fracture repair has shifted away from direct, anatomic reconstruction of osseous surfaces and now emphasizes restoration of length, rotation, and alignment, with preservation of local soft tissues. The use of percutaneous plating and nailing techniques has expanded to many regions of fracture care. Although minimally invasive reduction techniques are more difficult to perform, there is little reason to expect a return to traditional open surgical methods. Second, open tibial fractures remain problematic despite recent advances in fracture care. Prospective evaluation of patients with open tibial fractures and/or mangled extremities in the Lower Extremity Assessment Project (LEAP) showed that at two years, most patients had poor outcomes, with only half of the patients returning to work. By seven years, half of the patients continued to report appreciable disability, and only one in three had outcome scores typical of a general population. More recent prospectively acquired data about open tibial fractures, gathered from a randomized trial of the effects of bone morphogenetic protein (BMP), showed that one year after injury, more than half of the patients who were managed with the current standard of care had treatment failure. Third, outcomes research has exposed evidence of widespread psychological distress following musculoskeletal trauma. Multiple studies have documented high rates of psychological distress among patients with musculoskeletal trauma. Psychological distress is strongly associated with patient outcome--including functional outcome--following trauma. Despite this strong association, no study evaluating the ability of clinicians to treat psychological distress after musculoskeletal trauma has been reported in the literature to my knowledge as of the time of this writing, nor do orthopaedic studies routinely control for psychological distress when evaluating outcome. Psychological distress after trauma, with its large impact on trauma outcomes, remains a substantial problem that is usually ignored and untreated.

Entities:  

Mesh:

Year:  2008        PMID: 18292368     DOI: 10.2106/JBJS.G.01217

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  11 in total

1.  Development and validation of an instrument to predict functional recovery in tibial fracture patients: the Somatic Pre-Occupation and Coping (SPOC) questionnaire.

Authors:  Jason W Busse; Mohit Bhandari; Gordon H Guyatt; Diane Heels-Ansdell; Abhaya V Kulkarni; Scott Mandel; David Sanders; Emil Schemitsch; Mark Swiontkowski; Paul Tornetta; Eugene Wai; Stephen D Walter
Journal:  J Orthop Trauma       Date:  2012-06       Impact factor: 2.512

2.  The association of reamed intramedullary nailing and long-term cognitive impairment.

Authors:  Justin E Richards; Oscar D Guillamondegui; Kristin R Archer; James C Jackson; E Wesley Ely; William T Obremskey
Journal:  J Orthop Trauma       Date:  2011-12       Impact factor: 2.512

3.  Percutaneous Peripheral Nerve Stimulation to Control Postoperative Pain, Decrease Opioid Use, and Accelerate Functional Recovery Following Orthopedic Trauma.

Authors:  Brian M Ilfeld; Scott T Ball; Steven P Cohen; Steven R Hanling; Ian M Fowler; Amorn Wongsarnpigoon; Joseph W Boggs
Journal:  Mil Med       Date:  2019-03-01       Impact factor: 1.437

4.  Stem cell-based therapy for prevention of delayed fracture union: a randomized and prospective preliminary study.

Authors:  Meir Liebergall; Josh Schroeder; Rami Mosheiff; Zulma Gazit; Zilberman Yoram; Linda Rasooly; Anat Daskal; Amal Khoury; Yoram Weil; Shaul Beyth
Journal:  Mol Ther       Date:  2013-06-04       Impact factor: 11.454

5.  Secreted frizzled related protein 1 is a target to improve fracture healing.

Authors:  Tripti Gaur; John J Wixted; Sadiq Hussain; Shannon L O'Connell; Elise F Morgan; David C Ayers; Barry S Komm; Peter V Bodine; Gary S Stein; Jane B Lian
Journal:  J Cell Physiol       Date:  2009-07       Impact factor: 6.384

6.  Surgical site infection in high-energy peri-articular tibia fractures with intra-wound vancomycin powder: a retrospective pilot study.

Authors:  Keerat Singh; Jennifer M Bauer; Gregory Y LaChaud; Jesse E Bible; Hassan R Mir
Journal:  J Orthop Traumatol       Date:  2015-05-10

7.  Bioactivity and osteointegration of hydroxyapatite-coated stainless steel and titanium wires used for intramedullary osteosynthesis.

Authors:  Arnold V Popkov; Elena N Gorbach; Natalia A Kononovich; Dmitry A Popkov; Sergey I Tverdokhlebov; Evgeniy V Shesterikov
Journal:  Strategies Trauma Limb Reconstr       Date:  2017-04-06

8.  Percutaneous Autologous Bone Marrow-Derived Mesenchymal Stromal Cell Implantation Is Safe for Reconstruction of Human Lower Limb Long Bone Atrophic Nonunion.

Authors:  Mohsen Emadedin; Narges Labibzadeh; Roghayeh Fazeli; Fatemeh Mohseni; Seyedeh Esmat Hosseini; Reza Moghadasali; Soura Mardpour; Vajiheh Azimian; Alireza Goodarzi; Maede Ghorbani Liastani; Ali Mirazimi Bafghi; Mohamadreza Baghaban Eslaminejad; Nasser Aghdami
Journal:  Cell J       Date:  2016-12-21       Impact factor: 2.479

Review 9.  Recent Advances and Future of Gene Therapy for Bone Regeneration.

Authors:  Galina Shapiro; Raphael Lieber; Dan Gazit; Gadi Pelled
Journal:  Curr Osteoporos Rep       Date:  2018-08       Impact factor: 5.096

Review 10.  Orthopaedic traumatology: fundamental principles and current controversies for the acute care surgeon.

Authors:  Shad K Pharaon; Shawn Schoch; Lucas Marchand; Amer Mirza; John Mayberry
Journal:  Trauma Surg Acute Care Open       Date:  2018-01-08
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.