OBJECTIVES: To analyse the susceptibility pattern of a collection of Fusarium clinical isolates. METHODS: The antifungal susceptibility pattern of 67 isolates of Fusarium was analysed. Strains were identified by morphological and molecular methods by means of sequencing elongation factor alpha. RESULTS AND CONCLUSIONS: Six different species were identified. Fusarium solani was the most frequently isolated, followed by Fusarium oxysporum, Fusarium proliferatum and Fusarium verticilloides. Amphotericin B was the only drug with in vitro activity (range: 0.015-32 mg/L). The rest of the antifungals tested (itraconazole, voriconazole, ravuconazole, posaconazole and terbinafine) showed very poor activity against Fusarium, confirming the multiresistant nature of this genus.
OBJECTIVES: To analyse the susceptibility pattern of a collection of Fusarium clinical isolates. METHODS: The antifungal susceptibility pattern of 67 isolates of Fusarium was analysed. Strains were identified by morphological and molecular methods by means of sequencing elongation factor alpha. RESULTS AND CONCLUSIONS: Six different species were identified. Fusarium solani was the most frequently isolated, followed by Fusarium oxysporum, Fusarium proliferatum and Fusarium verticilloides. Amphotericin B was the only drug with in vitro activity (range: 0.015-32 mg/L). The rest of the antifungals tested (itraconazole, voriconazole, ravuconazole, posaconazole and terbinafine) showed very poor activity against Fusarium, confirming the multiresistant nature of this genus.
Authors: Kerry O'Donnell; Deanna A Sutton; Michael G Rinaldi; Brice A J Sarver; S Arunmozhi Balajee; Hans-Josef Schroers; Richard C Summerbell; Vincent A R G Robert; Pedro W Crous; Ning Zhang; Takayuki Aoki; Kyongyong Jung; Jongsun Park; Yong-Hwan Lee; Seogchan Kang; Bongsoo Park; David M Geiser Journal: J Clin Microbiol Date: 2010-08-04 Impact factor: 5.948
Authors: S A Balajee; A M Borman; M E Brandt; J Cano; M Cuenca-Estrella; E Dannaoui; J Guarro; G Haase; C C Kibbler; W Meyer; K O'Donnell; C A Petti; J L Rodriguez-Tudela; D Sutton; A Velegraki; B L Wickes Journal: J Clin Microbiol Date: 2008-12-10 Impact factor: 5.948
Authors: B Dalyan Cilo; A M S Al-Hatmi; S Seyedmousavi; A J M M Rijs; P E Verweij; B Ener; G S de Hoog; A D van Diepeningen Journal: Eur J Clin Microbiol Infect Dis Date: 2015-05-21 Impact factor: 3.267