| Literature DB >> 18259178 |
Jörg Romeis1, Detlef Bartsch, Franz Bigler, Marco P Candolfi, Marco M C Gielkens, Susan E Hartley, Richard L Hellmich, Joseph E Huesing, Paul C Jepson, Raymond Layton, Hector Quemada, Alan Raybould, Robyn I Rose, Joachim Schiemann, Mark K Sears, Anthony M Shelton, Jeremy Sweet, Zigfridas Vaituzis, Jeffrey D Wolt.
Abstract
An international initiative is developing a scientifically rigorous approach to evaluate the potential risks to nontarget arthropods (NTAs) posed by insect-resistant, genetically modified (IRGM) crops. It adapts the tiered approach to risk assessment that is used internationally within regulatory toxicology and environmental sciences. The approach focuses on the formulation and testing of clearly stated risk hypotheses, making maximum use of available data and using formal decision guidelines to progress between testing stages (or tiers). It is intended to provide guidance to regulatory agencies that are currently developing their own NTA risk assessment guidelines for IRGM crops and to help harmonize regulatory requirements between different countries and different regions of the world.Mesh：
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Year: 2008 PMID： 18259178 DOI： 10.1038/nbt1381
Source DB: PubMed Journal: Nat Biotechnol ISSN： 1087-0156 Impact factor: 54.908