OBJECTIVE: To examine the association between gestational weight gain and adverse maternal and infant outcomes among overweight women [body mass index (BMI) 26.0-29.0 kg/m(2)]. METHODS: A population-based cohort study using birth certificate data (1990-2004) from 34,143 singleton, full-term deliveries to nulliparous, Missouri residents ages 18-35. Gestational weight gain was divided into three categories: below Institute of Medicine (IOM) recommendations (<15 lbs), within IOM recommendations (15-25 lbs), and above IOM recommendations (>25 lbs). Categories of 10-lb increments were also evaluated. The primary outcomes were preeclampsia, cesarean section, macrosomia, low birth weight (LBW), and perinatal death. Adjusted relative risks and 95% confidence intervals (CI) were calculated using Mantel-Haenszel pooled estimator. RESULTS: Compared to women who gained 15-25 lbs, women who gained <15 lbs were 0.8 (95% CI 0.6-1.0), 0.9 (0.8-1.0), 0.6 (0.5-0.8), and 1.7 (1.4-2.2) times as likely to have preeclampsia, cesarean section, macrosomia, and LBW, respectively. Conversely, women who gained >25 lbs were 1.7 (1.5-1.9), 1.3 (1.2-1.4), 2.1 (1.9-2.3), and 0.6 (0.5-0.7) times as likely to have preeclampsia, cesarean section, macrosomia, and LBW, respectively. The lowest risk of adverse outcomes was for women who gained in the 6-14 and 15-24 lb categories. There was no association between gestational weight gain and perinatal death. CONCLUSIONS: Increasing gestational weight gain appears to decrease the risk of LBW but elevates the risks of preeclampsia, cesarean section, and macrosomia. Overweight women should gain within current IOM recommendations.
OBJECTIVE: To examine the association between gestational weight gain and adverse maternal and infant outcomes among overweight women [body mass index (BMI) 26.0-29.0 kg/m(2)]. METHODS: A population-based cohort study using birth certificate data (1990-2004) from 34,143 singleton, full-term deliveries to nulliparous, Missouri residents ages 18-35. Gestational weight gain was divided into three categories: below Institute of Medicine (IOM) recommendations (<15 lbs), within IOM recommendations (15-25 lbs), and above IOM recommendations (>25 lbs). Categories of 10-lb increments were also evaluated. The primary outcomes were preeclampsia, cesarean section, macrosomia, low birth weight (LBW), and perinatal death. Adjusted relative risks and 95% confidence intervals (CI) were calculated using Mantel-Haenszel pooled estimator. RESULTS: Compared to women who gained 15-25 lbs, women who gained <15 lbs were 0.8 (95% CI 0.6-1.0), 0.9 (0.8-1.0), 0.6 (0.5-0.8), and 1.7 (1.4-2.2) times as likely to have preeclampsia, cesarean section, macrosomia, and LBW, respectively. Conversely, women who gained >25 lbs were 1.7 (1.5-1.9), 1.3 (1.2-1.4), 2.1 (1.9-2.3), and 0.6 (0.5-0.7) times as likely to have preeclampsia, cesarean section, macrosomia, and LBW, respectively. The lowest risk of adverse outcomes was for women who gained in the 6-14 and 15-24 lb categories. There was no association between gestational weight gain and perinatal death. CONCLUSIONS: Increasing gestational weight gain appears to decrease the risk of LBW but elevates the risks of preeclampsia, cesarean section, and macrosomia. Overweight women should gain within current IOM recommendations.
Authors: Patricia M Dietz; William M Callaghan; Mary E Cogswell; Brian Morrow; Cynthia Ferre; Laura A Schieve Journal: Epidemiology Date: 2006-03 Impact factor: 4.822
Authors: Ellis Voerman; Susana Santos; Hazel Inskip; Pilar Amiano; Henrique Barros; Marie-Aline Charles; Leda Chatzi; George P Chrousos; Eva Corpeleijn; Sarah Crozier; Myriam Doyon; Merete Eggesbø; Maria Pia Fantini; Sara Farchi; Francesco Forastiere; Vagelis Georgiu; Davide Gori; Wojciech Hanke; Irva Hertz-Picciotto; Barbara Heude; Marie-France Hivert; Daniel Hryhorczuk; Carmen Iñiguez; Anne M Karvonen; Leanne K Küpers; Hanna Lagström; Debbie A Lawlor; Irina Lehmann; Per Magnus; Renata Majewska; Johanna Mäkelä; Yannis Manios; Monique Mommers; Camilla S Morgen; George Moschonis; Ellen A Nohr; Anne-Marie Nybo Andersen; Emily Oken; Agnieszka Pac; Eleni Papadopoulou; Juha Pekkanen; Costanza Pizzi; Kinga Polanska; Daniela Porta; Lorenzo Richiardi; Sheryl L Rifas-Shiman; Nel Roeleveld; Luca Ronfani; Ana C Santos; Marie Standl; Hein Stigum; Camilla Stoltenberg; Elisabeth Thiering; Carel Thijs; Maties Torrent; Tomas Trnovec; Marleen M H J van Gelder; Lenie van Rossem; Andrea von Berg; Martine Vrijheid; Alet Wijga; Oleksandr Zvinchuk; Thorkild I A Sørensen; Keith Godfrey; Vincent W V Jaddoe; Romy Gaillard Journal: JAMA Date: 2019-05-07 Impact factor: 56.272
Authors: Lisa M Bodnar; Lara L Siminerio; Katherine P Himes; Jennifer A Hutcheon; Timothy L Lash; Sara M Parisi; Barbara Abrams Journal: Obesity (Silver Spring) Date: 2015-11-17 Impact factor: 5.002