Literature DB >> 18212129

Action-blindsight in healthy subjects after transcranial magnetic stimulation.

Mark Schram Christensen1, Lasse Kristiansen, James B Rowe, Jens Bo Nielsen.   

Abstract

Clinical cases of blindsight have shown that visually guided movements can be accomplished without conscious visual perception. Here, we show that blindsight can be induced in healthy subjects by using transcranial magnetic stimulation over the visual cortex. Transcranial magnetic stimulation blocked the conscious perception of a visual stimulus, but subjects still corrected an ongoing reaching movement in response to the stimulus. The data show that correction of reaching movements does not require conscious perception of a visual target stimulus, even in healthy people. Our results support previous results suggesting that an efference copy is involved in movement correction, and this mechanism seems to be consistent even for movement correction without perception.

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Year:  2008        PMID: 18212129      PMCID: PMC2234142          DOI: 10.1073/pnas.0705858105

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  22 in total

1.  Disynaptic pyramidal excitation in forelimb motoneurons mediated via C(3)-C(4) propriospinal neurons in the Macaca fuscata.

Authors:  B Alstermark; T Isa; Y Ohki; Y Saito
Journal:  J Neurophysiol       Date:  1999-12       Impact factor: 2.714

Review 2.  Neural correlates of consciousness in humans.

Authors:  Geraint Rees; Gabriel Kreiman; Christof Koch
Journal:  Nat Rev Neurosci       Date:  2002-04       Impact factor: 34.870

3.  Efference copy in the control of movement.

Authors:  R W Angel
Journal:  Neurology       Date:  1976-12       Impact factor: 9.910

Review 4.  The Theory of Event Coding (TEC): a framework for perception and action planning.

Authors:  B Hommel; J Müsseler; G Aschersleben; W Prinz
Journal:  Behav Brain Sci       Date:  2001-10       Impact factor: 12.579

Review 5.  The C3-C4 propriospinal system in the cat and monkey: a spinal pre-motoneuronal centre for voluntary motor control.

Authors:  B Alstermark; T Isa; L-G Pettersson; S Sasaki
Journal:  Acta Physiol (Oxf)       Date:  2007-02       Impact factor: 6.311

6.  Suppression of visual perception by magnetic coil stimulation of human occipital cortex.

Authors:  V E Amassian; R Q Cracco; P J Maccabee; J B Cracco; A Rudell; L Eberle
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1989 Nov-Dec

7.  Visual capacity in the hemianopic field following a restricted occipital ablation.

Authors:  L Weiskrantz; E K Warrington; M D Sanders; J Marshall
Journal:  Brain       Date:  1974-12       Impact factor: 13.501

8.  "Blindsight": Vision in a field defect.

Authors:  M D Sanders; E K Warrington; J Marshall; L Wieskrantz
Journal:  Lancet       Date:  1974-04-20       Impact factor: 79.321

9.  Evidence for subcortical involvement in the visual control of human reaching.

Authors:  B L Day; P Brown
Journal:  Brain       Date:  2001-09       Impact factor: 13.501

Review 10.  Eye movement control by the cerebral cortex.

Authors:  Charles Pierrot-Deseilligny; Dan Milea; René M Müri
Journal:  Curr Opin Neurol       Date:  2004-02       Impact factor: 5.710

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  7 in total

1.  Frontal Monitoring and Parietal Evidence: Mechanisms of Error Correction.

Authors:  Ana Navarro-Cebrian; Robert T Knight; Andrew S Kayser
Journal:  J Cogn Neurosci       Date:  2016-03-30       Impact factor: 3.225

Review 2.  Using brain stimulation to disentangle neural correlates of conscious vision.

Authors:  Tom A de Graaf; Alexander T Sack
Journal:  Front Psychol       Date:  2014-09-23

3.  Who's afraid of response bias?

Authors:  Megan A K Peters; Tony Ro; Hakwan Lau
Journal:  Neurosci Conscious       Date:  2016-02-27

4.  Subconscious visual cues during movement execution allow correct online choice reactions.

Authors:  Christian Leukel; Jesper Lundbye-Jensen; Mark Schram Christensen; Albert Gollhofer; Jens Bo Nielsen; Wolfgang Taube
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240

5.  Brain-stimulation induced blindsight: unconscious vision or response bias?

Authors:  David A Lloyd; Arman Abrahamyan; Justin A Harris
Journal:  PLoS One       Date:  2013-12-06       Impact factor: 3.240

6.  Behavior in oblivion: the neurobiology of subliminal priming.

Authors:  Christianne Jacobs; Alexander T Sack
Journal:  Brain Sci       Date:  2012-05-29

Review 7.  Behavioral Consequences and Cortical Reorganization in Homonymous Hemianopia.

Authors:  Sylvie Chokron; Céline Perez; Carole Peyrin
Journal:  Front Syst Neurosci       Date:  2016-06-28
  7 in total

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