Literature DB >> 18205159

Heterobivalent ligands crosslink multiple cell-surface receptors: the human melanocortin-4 and delta-opioid receptors.

Josef Vagner1, Liping Xu, Heather L Handl, Jatinder S Josan, David L Morse, Eugene A Mash, Robert J Gillies, Victor J Hruby.   

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Year:  2008        PMID： 18205159      PMCID： PMC2716288          DOI： 10.1002/anie.200702770

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  17 in total

1.  Molecular architecture and evolution of a modular spider silk protein gene.

Authors:  C Y Hayashi; R V Lewis
Journal:  Science       Date:  2000-02-25       Impact factor: 47.728

2.  Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH.

Authors:  Josef Vagner; Heather L Handl; Robert J Gillies; Victor J Hruby
Journal:  Bioorg Med Chem Lett       Date:  2004-01-05       Impact factor: 2.823

3.  Multivalent melanotropic peptide and fluorescent macromolecular conjugates: new reagents for characterization of melanotropin receptors.

Authors:  S D Sharma; M E Granberry; J Jiang; S P Leong; M E Hadley; V J Hruby
Journal:  Bioconjug Chem       Date:  1994 Nov-Dec       Impact factor: 4.774

4.  CD spectra of indolicidin antimicrobial peptides suggest turns, not polyproline helix.

Authors:  A S Ladokhin; M E Selsted; S H White
Journal:  Biochemistry       Date:  1999-09-21       Impact factor: 3.162

Review 5.  Untangling the ErbB signalling network.

Authors:  Y Yarden; M X Sliwkowski
Journal:  Nat Rev Mol Cell Biol       Date:  2001-02       Impact factor: 94.444

6.  Melanotropic peptide-conjugated beads for microscopic visualization and characterization of melanoma melanotropin receptors.

Authors:  S D Sharma; J Jiang; M E Hadley; D L Bentley; V J Hruby
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-26       Impact factor: 11.205

7.  Lanthanide-based time-resolved fluorescence of in cyto ligand-receptor interactions.

Authors:  Heather L Handl; Josef Vagner; Henry I Yamamura; Victor J Hruby; Robert J Gillies
Journal:  Anal Biochem       Date:  2004-07-15       Impact factor: 3.365

8.  Synthesis and evaluation of bivalent NDP-alpha-MSH(7) peptide ligands for binding to the human melanocortin receptor 4 (hMC4R).

Authors:  Heather L Handl; Rajesh Sankaranarayanan; Jatinder S Josan; Josef Vagner; Eugene A Mash; Robert J Gillies; Victor J Hruby
Journal:  Bioconjug Chem       Date:  2007-06-26       Impact factor: 4.774

9.  A polymer scaffold for protein oligomerization.

Authors:  Byron R Griffith; Benjamin L Allen; Alan C Rapraeger; Laura L Kiessling
Journal:  J Am Chem Soc       Date:  2004-02-18       Impact factor: 15.419

Review 10.  Structure and biological activity of basement membrane proteins.

Authors:  R Timpl
Journal:  Eur J Biochem       Date:  1989-04-01
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  38 in total

1.  Cell-specific targeting by heterobivalent ligands.

Authors:  Jatinder S Josan; Heather L Handl; Rajesh Sankaranarayanan; Liping Xu; Ronald M Lynch; Josef Vagner; Eugene A Mash; Victor J Hruby; Robert J Gillies
Journal:  Bioconjug Chem       Date:  2011-06-16       Impact factor: 4.774

2.  A sucrose-derived scaffold for multimerization of bioactive peptides.

Authors:  Venkataramanarao Rao; Ramesh Alleti; Liping Xu; Narges K Tafreshi; David L Morse; Robert J Gillies; Eugene A Mash
Journal:  Bioorg Med Chem       Date:  2011-08-27       Impact factor: 3.641

Review 3.  The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases.

Authors:  Minying Cai; Victor J Hruby
Journal:  Curr Protein Pept Sci       Date:  2016       Impact factor: 3.272

4.  Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand.

Authors:  Natalie M Barkey; Narges K Tafreshi; Jatinder S Josan; Channa R De Silva; Kevin N Sill; Victor J Hruby; Robert J Gillies; David L Morse; Josef Vagner
Journal:  J Med Chem       Date:  2011-11-10       Impact factor: 7.446

5.  Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.

Authors:  Jatinder S Josan; Channa R De Silva; Byunghee Yoo; Ronald M Lynch; Mark D Pagel; Josef Vagner; Victor J Hruby
Journal:  Methods Mol Biol       Date:  2011

6.  Design, synthesis, and biological studies of efficient multivalent melanotropin ligands: tools toward melanoma diagnosis and treatment.

Authors:  Nabila Brabez; Ronald M Lynch; Liping Xu; Robert J Gillies; Gerard Chassaing; Solange Lavielle; Victor J Hruby
Journal:  J Med Chem       Date:  2011-10-03       Impact factor: 7.446

7.  Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy.

Authors:  Amanda Shanks Huynh; Woo Jin Chung; Hyun-Il Cho; Valerie E Moberg; Esteban Celis; David L Morse; Josef Vagner
Journal:  J Med Chem       Date:  2012-11-08       Impact factor: 7.446

Review 8.  Organic chemistry and biology: chemical biology through the eyes of collaboration.

Authors:  Victor J Hruby
Journal:  J Org Chem       Date:  2009-12-18       Impact factor: 4.354

9.  An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.

Authors:  Cody J Lensing; Katie T Freeman; Sathya M Schnell; Danielle N Adank; Robert C Speth; Carrie Haskell-Luevano
Journal:  J Med Chem       Date:  2016-03-29       Impact factor: 7.446

10.  Adventures in peptides and science with students! The joys of research.

Authors:  Victor J Hruby
Journal:  Biopolymers       Date:  2013-04       Impact factor: 2.505
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