Literature DB >> 18199632

Insight into neurocognitive dysfunction in schizophrenia.

Alice Medalia1, Julie Thysen.   

Abstract

Insight into psychotic symptoms is typically poor in schizophrenia; however, it is not known whether insight into neurocognitive impairment is similarly impaired. Most people with schizophrenia experience cognitive dysfunction, and the deficits in attention, memory, and critical thinking have been associated with poor functional outcome. As new treatments are developed for the cognitive impairments, it will be important to know whether patients will be receptive to yet another therapy. Insight is an important factor in treatment compliance and treatment outcome; however, it is not known if patients have insight into their cognitive dysfunction. In order to assess insight into neuro cognitive dysfunction, 75 subjects were administered the Measure of Insight into Cognition-Clinician Rated, a newly created measure based on the Scale to Access the Unawareness of Mental Disorder, that assesses insight into cognitive impairment. Subjects were also administered the Brief Assessment of Cognition in Schizophrenia and Independent Living Scale-Problem Solving to objectively assess neuropsychological status and problem-solving skills needed for independent living. Results demonstrated that virtually all subjects had cognitive impairment, yet insight into their neuro cognitive symptoms was limited. This finding has potential implications for treatment programs seeking to improve cognitive functioning in schizophrenia.

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Year:  2008        PMID: 18199632      PMCID: PMC2632502          DOI: 10.1093/schbul/sbm144

Source DB:  PubMed          Journal:  Schizophr Bull        ISSN: 0586-7614            Impact factor:   9.306


  32 in total

Review 1.  Unawareness of deficits in neuropsychological syndromes.

Authors:  S M McGlynn; D L Schacter
Journal:  J Clin Exp Neuropsychol       Date:  1989-03       Impact factor: 2.475

2.  Defining a cognitive function decrement in schizophrenia.

Authors:  Richard S E Keefe; Charles E Eesley; Margaret P Poe
Journal:  Biol Psychiatry       Date:  2005-03-15       Impact factor: 13.382

3.  Early insight predicts depression and attempted suicide after 4 years in first-episode schizophrenia and schizophreniform disorder.

Authors:  N Crumlish; P Whitty; M Kamali; M Clarke; S Browne; O McTigue; A Lane; A Kinsella; C Larkin; E O'Callaghan
Journal:  Acta Psychiatr Scand       Date:  2005-12       Impact factor: 6.392

Review 4.  Disease, deficit or denial? Models of poor insight in psychosis.

Authors:  M A Cooke; E R Peters; E Kuipers; V Kumari
Journal:  Acta Psychiatr Scand       Date:  2005-07       Impact factor: 6.392

5.  Interpreting patient/informant discrepancies of reported cognitive symptoms in MS.

Authors:  D A Carone; R H B Benedict; F E Munschauer; I Fishman; B Weinstock-Guttman
Journal:  J Int Neuropsychol Soc       Date:  2005-09       Impact factor: 2.892

6.  The independent living scales as a measure of functional outcome for schizophrenia.

Authors:  Nadine Revheim; Alice Medalia
Journal:  Psychiatr Serv       Date:  2004-09       Impact factor: 3.084

7.  A comparison between an interview and a self-report method of insight assessment in chronic schizophrenia.

Authors:  Donald A Young; Zachariah Campbell; Konstantine K Zakzanis; Earl Weinstein
Journal:  Schizophr Res       Date:  2003-09-01       Impact factor: 4.939

8.  The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery.

Authors:  Richard S E Keefe; Terry E Goldberg; Philip D Harvey; James M Gold; Margaret P Poe; Leigh Coughenour
Journal:  Schizophr Res       Date:  2004-06-01       Impact factor: 4.939

9.  Suicidality and psychosis: the predictive potential of symptomatology and insight into illness.

Authors:  Robert C Schwartz; Shannon D Smith
Journal:  J Psychiatr Res       Date:  2004 Mar-Apr       Impact factor: 4.791

Review 10.  What are the functional consequences of neurocognitive deficits in schizophrenia?

Authors:  M F Green
Journal:  Am J Psychiatry       Date:  1996-03       Impact factor: 18.112

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  27 in total

1.  Clinical and Cognitive Insight in a Compensatory Cognitive Training Intervention.

Authors:  Cynthia Z Burton; Lea Vella; Elizabeth W Twamley
Journal:  Am J Psychiatr Rehabil       Date:  2011-10-01

2.  Self-assessment in schizophrenia: Accuracy of evaluation of cognition and everyday functioning.

Authors:  Felicia Gould; Laura Stone McGuire; Dante Durand; Samir Sabbag; Carlos Larrauri; Thomas L Patterson; Elizabeth W Twamley; Philip D Harvey
Journal:  Neuropsychology       Date:  2015-02-02       Impact factor: 3.295

3.  Predictors of the accuracy of self assessment of everyday functioning in people with schizophrenia.

Authors:  Samir Sabbag; Elizabeth W Twamley; Lea Vella; Robert K Heaton; Thomas L Patterson; Philip D Harvey
Journal:  Schizophr Res       Date:  2012-03-02       Impact factor: 4.939

Review 4.  Insight in schizophrenia: a review.

Authors:  Marjorie Baier
Journal:  Curr Psychiatry Rep       Date:  2010-08       Impact factor: 5.285

Review 5.  The effects of aging on insight into illness in schizophrenia: a review.

Authors:  Philip Gerretsen; Eric Plitman; Tarek K Rajji; Ariel Graff-Guerrero
Journal:  Int J Geriatr Psychiatry       Date:  2014-07-23       Impact factor: 3.485

6.  Compensatory cognitive training for psychosis: who benefits? Who stays in treatment?

Authors:  Elizabeth W Twamley; Cynthia Z Burton; Lea Vella
Journal:  Schizophr Bull       Date:  2011-09       Impact factor: 9.306

7.  Impaired introspective accuracy in schizophrenia: an independent predictor of functional outcomes.

Authors:  Juliet Silberstein; Philip D Harvey
Journal:  Cogn Neuropsychiatry       Date:  2018-11-26       Impact factor: 1.871

8.  Compensatory cognitive training for psychosis: effects in a randomized controlled trial.

Authors:  Elizabeth W Twamley; Lea Vella; Cynthia Z Burton; Robert K Heaton; Dilip V Jeste
Journal:  J Clin Psychiatry       Date:  2012-08-07       Impact factor: 4.384

9.  Assessment of everyday functioning in schizophrenia.

Authors:  Philip D Harvey
Journal:  Innov Clin Neurosci       Date:  2011-05

10.  Self-assessment of functional ability in schizophrenia: milestone achievement and its relationship to accuracy of self-evaluation.

Authors:  Felicia Gould; Samir Sabbag; Dante Durand; Thomas L Patterson; Philip D Harvey
Journal:  Psychiatry Res       Date:  2013-03-26       Impact factor: 3.222

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