Literature DB >> 15952940

Disease, deficit or denial? Models of poor insight in psychosis.

M A Cooke1, E R Peters, E Kuipers, V Kumari.   

Abstract

OBJECTIVE: To examine the evidence for the three kinds of aetiological model that dominate the current literature on poor insight in psychosis: clinical models, the neuropsychological model, and the psychological denial model.
METHOD: Studies pertaining to one or more of these aetiological models were identified, reviewed and critically evaluated.
RESULTS: There is little support for clinical models, partly because they lack testable hypotheses. Several studies reveal a positive relationship between insight and executive function, which may be related to frontal lobe dysfunction. However, the extent to which this relationship is specific and independent of general cognitive impairment remains unclear. There is tentative evidence to support the psychological denial model. Recent data combining the latter two approaches suggest that multiple factors contribute to poor insight.
CONCLUSION: Integration of different aetiological models is necessary for a fuller understanding of insight in psychosis. Future research should assess multiple aetiological mechanisms in single investigations. Copyright Blackwell Munksgaard 2005.

Entities:  

Mesh:

Year:  2005        PMID: 15952940     DOI: 10.1111/j.1600-0447.2005.00537.x

Source DB:  PubMed          Journal:  Acta Psychiatr Scand        ISSN: 0001-690X            Impact factor:   6.392


  31 in total

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3.  Cognitive function and competitive employment in schizophrenia: relative contribution of insight and psychopathology.

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Journal:  Community Ment Health J       Date:  2014-07-27

5.  Theory of mind and unawareness of illness in schizophrenia: is poor insight a mentalizing deficit?

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7.  Lack of relationship between psychological denial and unawareness of illness in schizophrenia-spectrum disorders.

Authors:  Carrie L Kruck; Laura A Flashman; Robert M Roth; Nancy S Koven; Thomas W McAllister; Andrew J Saykin
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Authors:  A Karow; F-G Pajonk; J Reimer; F Hirdes; C Osterwald; D Naber; S Moritz
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-04       Impact factor: 5.270

9.  Neurological basis of poor insight in psychosis: a voxel-based MRI study.

Authors:  Michael A Cooke; Dominic Fannon; Elizabeth Kuipers; Emmanuelle Peters; Steven C Williams; Veena Kumari
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10.  Insight, distress and coping styles in schizophrenia.

Authors:  Michael Cooke; Emmanuelle Peters; Dominic Fannon; Anantha P P Anilkumar; Ingrid Aasen; Elizabeth Kuipers; Veena Kumari
Journal:  Schizophr Res       Date:  2007-06-11       Impact factor: 4.939

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