Literature DB >> 18199412

HIV-1 hides an Achilles' heel in virion lipids.

Barton F Haynes1, S Munir Alam.   

Abstract

In this issue, Sun et al. (2008) model the interface between a neutralizing antibody and HIV-1 glycoprotein 41 (gp41) envelope peptide in lipids. This model could help overcome a roadblock in HIV-1 vaccine development.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18199412      PMCID： PMC2673567          DOI： 10.1016/j.immuni.2007.12.005

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  10 in total

Review 1.  Mechanisms of viral membrane fusion and its inhibition.

Authors:  D M Eckert; P S Kim
Journal:  Annu Rev Biochem       Date:  2001       Impact factor: 23.643

Review 2.  Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.

Authors:  Barton F Haynes; David C Montefiori
Journal:  Expert Rev Vaccines       Date:  2006-08       Impact factor: 5.217

3.  Atomic structure of the ectodomain from HIV-1 gp41.

Authors:  W Weissenhorn; A Dessen; S C Harrison; J J Skehel; D C Wiley
Journal:  Nature       Date:  1997-05-22       Impact factor: 49.962

4.  Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41.

Authors:  Rosa M F Cardoso; Michael B Zwick; Robyn L Stanfield; Renate Kunert; James M Binley; Hermann Katinger; Dennis R Burton; Ian A Wilson
Journal:  Immunity       Date:  2005-02       Impact factor: 31.745

5.  The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.

Authors:  S Munir Alam; Mildred McAdams; David Boren; Michael Rak; Richard M Scearce; Feng Gao; Zenaido T Camacho; Daniel Gewirth; Garnett Kelsoe; Pojen Chen; Barton F Haynes
Journal:  J Immunol       Date:  2007-04-01       Impact factor: 5.422

6.  Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

Authors:  Barton F Haynes; Judith Fleming; E William St Clair; Herman Katinger; Gabriela Stiegler; Renate Kunert; James Robinson; Richard M Scearce; Kelly Plonk; Herman F Staats; Thomas L Ortel; Hua-Xin Liao; S Munir Alam
Journal:  Science       Date:  2005-04-28       Impact factor: 47.728

7.  Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development.

Authors:  E Meffre; M Milili; C Blanco-Betancourt; H Antunes; M C Nussenzweig; C Schiff
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

8.  An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.

Authors:  Josh D Nelson; Florence M Brunel; Richard Jensen; Emma T Crooks; Rosa M F Cardoso; Meng Wang; Ann Hessell; Ian A Wilson; James M Binley; Philip E Dawson; Dennis R Burton; Michael B Zwick
Journal:  J Virol       Date:  2007-02-07       Impact factor: 5.103

9.  HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane.

Authors:  Zhen-Yu J Sun; Kyoung Joon Oh; Mikyung Kim; Jessica Yu; Vladimir Brusic; Likai Song; Zhisong Qiao; Jia-huai Wang; Gerhard Wagner; Ellis L Reinherz
Journal:  Immunity       Date:  2008-01       Impact factor: 31.745

10.  Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope.

Authors:  Gilad Ofek; Min Tang; Anna Sambor; Hermann Katinger; John R Mascola; Richard Wyatt; Peter D Kwong
Journal:  J Virol       Date:  2004-10       Impact factor: 5.103
  10 in total
  14 in total

1.  Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.

Authors:  Nathan I Nicely; S Moses Dennison; Leonard Spicer; Richard M Scearce; Garnett Kelsoe; Yoshihiro Ueda; Haiyan Chen; Hua-Xin Liao; S Munir Alam; Barton F Haynes
Journal:  Nat Struct Mol Biol       Date:  2010-11-14       Impact factor: 15.369

2.  New cholesterol-specific antibodies remodel HIV-1 target cells' surface and inhibit their in vitro virus production.

Authors:  Zoltán Beck; Andrea Balogh; Andrea Kis; Emese Izsépi; László Cervenak; Glória László; Adrienn Bíró; Károly Liliom; Gábor Mocsár; György Vámosi; George Füst; Janos Matko
Journal:  J Lipid Res       Date:  2009-08-04       Impact factor: 5.922

3.  Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination.

Authors:  Vincent J Venditto; Douglas S Watson; Michael Motion; David Montefiori; Francis C Szoka
Journal:  Clin Vaccine Immunol       Date:  2012-10-31

Review 4.  Progress in HIV-1 vaccine development.

Authors:  Barton F Haynes; M Anthony Moody; Munir Alam; Mattia Bonsignori; Laurent Verkoczy; Guido Ferrari; Feng Gao; Georgia D Tomaras; Hua-Xin Liao; Garnett Kelsoe
Journal:  J Allergy Clin Immunol       Date:  2014-06-26       Impact factor: 10.793

5.  GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates.

Authors:  Emma L Mohr; Jinhua Xiang; James H McLinden; Thomas M Kaufman; Qing Chang; David C Montefiori; Donna Klinzman; Jack T Stapleton
Journal:  J Immunol       Date:  2010-09-08       Impact factor: 5.422

Review 6.  GB virus C: the good boy virus?

Authors:  Nirjal Bhattarai; Jack T Stapleton
Journal:  Trends Microbiol       Date:  2012-02-08       Impact factor: 17.079

7.  Stable docking of neutralizing human immunodeficiency virus type 1 gp41 membrane-proximal external region monoclonal antibodies 2F5 and 4E10 is dependent on the membrane immersion depth of their epitope regions.

Authors:  S Moses Dennison; Shelley M Stewart; Kathryn C Stempel; Hua-Xin Liao; Barton F Haynes; S Munir Alam
Journal:  J Virol       Date:  2009-07-29       Impact factor: 5.103

8.  Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbits.

Authors:  Vincent J Venditto; Lindsay Wieczorek; Sebastian Molnar; Fernando Teque; Gary Landucci; Douglas S Watson; Donald Forthal; Victoria R Polonis; Jay A Levy; Francis C Szoka
Journal:  Clin Vaccine Immunol       Date:  2014-05-28

9.  Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41.

Authors:  Douglas S Watson; Francis C Szoka
Journal:  Vaccine       Date:  2009-06-09       Impact factor: 3.641

10.  Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.

Authors:  Laurent Verkoczy; M Anthony Moody; T Matt Holl; Hilary Bouton-Verville; Richard M Scearce; Jennifer Hutchinson; S Munir Alam; Garnett Kelsoe; Barton F Haynes
Journal:  PLoS One       Date:  2009-10-06       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.