Literature DB >> 18181950

Stem cells and genetic disease.

A Mackay-Sim1, P Silburn.   

Abstract

Stem cell research is now a very broad field encompassing cells derived from all stages of life from the embryonic stem cells of the early blastocyst through to the adult stem cells of many tissues of the body. Adult stem cells from a variety of tissues are proving to be pluripotent and can differentiate into cell types different from the tissues from which they derive. Pre-clinical animal models indicate that adult stem cells do not cause tumours, not even, teratomas when transplanted. These properties, combined with the possibility of autologous transplantation, indicate significant advantages over embryonic stem cells in many proposed clinical applications.

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Year:  2008        PMID: 18181950      PMCID: PMC6496804          DOI: 10.1111/j.1365-2184.2008.00487.x

Source DB:  PubMed          Journal:  Cell Prolif        ISSN: 0960-7722            Impact factor:   6.831


  29 in total

1.  Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.

Authors:  T Wakayama; V Tabar; I Rodriguez; A C Perry; L Studer; P Mombaerts
Journal:  Science       Date:  2001-04-27       Impact factor: 47.728

Review 2.  Gene-environment interactions in sporadic Parkinson's disease.

Authors:  Liat Benmoyal-Segal; Hermona Soreq
Journal:  J Neurochem       Date:  2006-06       Impact factor: 5.372

Review 3.  Recent advances in globin gene transfer for the treatment of beta-thalassemia and sickle cell anemia.

Authors:  Michel Sadelain
Journal:  Curr Opin Hematol       Date:  2006-05       Impact factor: 3.284

Review 4.  Heterozygosity for a Mendelian disorder as a risk factor for complex disease.

Authors:  E Sidransky
Journal:  Clin Genet       Date:  2006-10       Impact factor: 4.438

Review 5.  Gene therapy for immunodeficiency diseases.

Authors:  Alain Fischer; Salima Hacein-Bey-Abina; Marina Cavazzana-Calvo
Journal:  Semin Hematol       Date:  2004-10       Impact factor: 3.851

Review 6.  Breast cancer susceptibility testing: past, present and future.

Authors:  Jessica I Goldberg; Patrick I Borgen
Journal:  Expert Rev Anticancer Ther       Date:  2006-08       Impact factor: 4.512

7.  Cell cycle alterations in biopsied olfactory neuroepithelium in schizophrenia and bipolar I disorder using cell culture and gene expression analyses.

Authors:  Richard D McCurdy; François Féron; Chris Perry; David C Chant; Duncan McLean; Nick Matigian; Nicholas K Hayward; John J McGrath; Alan Mackay-Sim
Journal:  Schizophr Res       Date:  2006-01-06       Impact factor: 4.939

Review 8.  Human embryonic stem cell culture: current limitations and novel strategies.

Authors:  N Findikli; N Z Candan; S Kahraman
Journal:  Reprod Biomed Online       Date:  2006-10       Impact factor: 3.828

Review 9.  The key role of adult stem cells: therapeutic perspectives.

Authors:  Augusto Pessina; Laura Gribaldo
Journal:  Curr Med Res Opin       Date:  2006-11       Impact factor: 2.580

Review 10.  Stem cells in tissue engineering.

Authors:  P Bianco; P G Robey
Journal:  Nature       Date:  2001-11-01       Impact factor: 49.962

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  1 in total

Review 1.  Neural stem cell niches in health and diseases.

Authors:  Ilaria Decimo; Francesco Bifari; Mauro Krampera; Guido Fumagalli
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

  1 in total

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