Literature DB >> 18181565

Multi-target-directed ligands to combat neurodegenerative diseases.

Andrea Cavalli1, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Vincenzo Tumiatti, Maurizio Recanatini, Carlo Melchiorre.   

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Year:  2008        PMID: 18181565     DOI: 10.1021/jm7009364

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  187 in total

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2.  Site-activated chelators derived from anti-Parkinson drug rasagiline as a potential safer and more effective approach to the treatment of Alzheimer's disease.

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Review 3.  Natural products as a source of Alzheimer's drug leads.

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Authors:  Mark Johnson; Tamara Antonio; Maarten E A Reith; Aloke K Dutta
Journal:  J Med Chem       Date:  2012-06-13       Impact factor: 7.446

5.  Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.

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Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-25       Impact factor: 11.205

6.  Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol.

Authors:  Catherine A S Deane; Ian R Brown
Journal:  Cell Stress Chaperones       Date:  2016-06-08       Impact factor: 3.667

Review 7.  Iron-chelating backbone coupled with monoamine oxidase inhibitory moiety as novel pluripotential therapeutic agents for Alzheimer's disease: a tribute to Moussa Youdim.

Authors:  Orly Weinreb; Silvia Mandel; Orit Bar-Am; Tamar Amit
Journal:  J Neural Transm (Vienna)       Date:  2011-03-01       Impact factor: 3.575

8.  Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease.

Authors:  Jie Gao; Bao-Ling Adam; Alvin V Terry
Journal:  Bioorg Med Chem Lett       Date:  2014-02-14       Impact factor: 2.823

9.  Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease.

Authors:  Bong-Suk Choi; Hyool Kim; Hyo Jeong Lee; Kumar Sapkota; Se Eun Park; Seung Kim; Sung-Jun Kim
Journal:  Neurochem Res       Date:  2013-11-09       Impact factor: 3.996

10.  sym-Triazines for directed multitarget modulation of cholinesterases and amyloid-β in Alzheimer's disease.

Authors:  Anthony J Veloso; Devjani Dhar; Ari M Chow; Biao Zhang; Derek W F Tang; Hashwin V S Ganesh; Svetlana Mikhaylichenko; Ian R Brown; Kagan Kerman
Journal:  ACS Chem Neurosci       Date:  2012-11-20       Impact factor: 4.418

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