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Literature DB >> 18179230

Synthesis of novel pyrimidine fused 8-membered heterocycles via iminium ion cyclization reactions.

Xin Che¹, Lianyou Zheng, Qun Dang, Xu Bai.

Abstract

Novel tricyclic pyrimidine-fused 8-membered heterocycles were prepared by an iminium ion cyclization using pyrimidinediamine systems with electron-rich aromatic rings.

Entities: Chemical

Mesh：

Substances：

Year: 2008 PMID： 18179230 DOI： 10.1021/jo7020746

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

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Cited

7 in total

1. Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach.

Authors: Jinbao Xiang; Zhuoqi Zhang; Yan Mu; Xianxiu Xu; Sigen Guo; Yongjin Liu; Daniel P Russo; Hao Zhu; Bing Yan; Xu Bai
Journal: ACS Comb Sci Date: 2016-04-15 Impact factor: 3.784

2. Synthesis of novel 4H-pyrimido[1,6-a]pyrimidines via a one-pot three-component condensation.

Authors: Jinbao Xiang; Hanghang Li; Kai Yang; Lang Yi; Yongnan Xu; Qun Dang; Xu Bai
Journal: Mol Divers Date: 2011-12-04 Impact factor: 2.943

3. Synthesis of highly substituted 2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-ones from 4,6-dichloro-5-formylpyrimidine, amines and aldehydes.

Authors: Jinbao Xiang; Chao Geng; Lang Yi; Qun Dang; Xu Bai
Journal: Mol Divers Date: 2011-04-21 Impact factor: 2.943

Review 4. Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid.

Authors: Elida N Thobokholt; Enrique L Larghi; Andrea B J Bracca; Teodoro S Kaufman
Journal: RSC Adv Date: 2020-05-19 Impact factor: 4.036

Synthesis of novel pyrimidine fused 8-membered heterocycles via iminium ion cyclization reactions.

1. Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach.

2. Synthesis of novel 4H-pyrimido[1,6-a]pyrimidines via a one-pot three-component condensation.

3. Synthesis of highly substituted 2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-ones from 4,6-dichloro-5-formylpyrimidine, amines and aldehydes.

Review 4. Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid.

5. N,N-Dimethyl-5-nitro-N,N-diphenyl-pyrimidine-4,6-diamine.

6. Mild and efficient cyanuric chloride catalyzed Pictet-Spengler reaction.

Review 7. The Pictet-Spengler Reaction Updates Its Habits.