Literature DB >> 18178772

Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation.

Mathieu Gissot1, Sang-Woon Choi, Reid F Thompson, John M Greally, Kami Kim.   

Abstract

Epigenetic factors play a role in the expression of virulence traits in Apicomplexa. Apicomplexan genomes encode putative DNA cytosine methylation enzymes. To assess the presence of cytosine methylation of Toxoplasma gondii and Cryptosporidium parvum DNA, we used mass spectrometry analysis and confirmed that these organisms lack detectable methylcytosine in their DNA.

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Year:  2008        PMID: 18178772      PMCID: PMC2268521          DOI: 10.1128/EC.00448-07

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN: 1535-9786


  19 in total

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Authors:  Melissa J Fazzari; John M Greally
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Authors:  Thomas J Templeton; Lakshminarayan M Iyer; Vivek Anantharaman; Shinichiro Enomoto; Juan E Abrahante; G M Subramanian; Stephen L Hoffman; Mitchell S Abrahamsen; L Aravind
Journal:  Genome Res       Date:  2004-09       Impact factor: 9.043

4.  Folate supplementation increases genomic DNA methylation in the liver of elder rats.

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Journal:  Br J Nutr       Date:  2005-01       Impact factor: 3.718

5.  A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry.

Authors:  Simonetta Friso; Sang-Woon Choi; Gregory G Dolnikowski; Jacob Selhub
Journal:  Anal Chem       Date:  2002-09-01       Impact factor: 6.986

6.  DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.

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7.  Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium.

Authors:  Sang-Woon Choi; Simonetta Friso; Haifa Ghandour; Pamela J Bagley; Jacob Selhub; Joel B Mason
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8.  Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite Entamoeba histolytica.

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10.  Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii.

Authors:  Mathieu Gissot; Krystyna A Kelly; James W Ajioka; John M Greally; Kami Kim
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  31 in total

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2.  An analytical pipeline for genomic representations used for cytosine methylation studies.

Authors:  Reid F Thompson; Mark Reimers; Batbayar Khulan; Mathieu Gissot; Todd A Richmond; Quan Chen; Xin Zheng; Kami Kim; John M Greally
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3.  Toxoplasma gondii presentations at the 10th International Workshops on Opportunistic Protists: 100 years and counting.

Authors:  Sandra K Halonen; Louis M Weiss
Journal:  Eukaryot Cell       Date:  2009-01-23

Review 4.  A decade of epigenetic research in Toxoplasma gondii.

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Journal:  Methods       Date:  2010-04-29       Impact factor: 3.608

Review 6.  Innate immunity to Toxoplasma gondii infection.

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7.  Genome-wide mapping of DNA methylation in the human malaria parasite Plasmodium falciparum.

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Journal:  Cell Host Microbe       Date:  2013-12-11       Impact factor: 21.023

Review 8.  New eukaryotic systematics: a phylogenetic perspective of developmental gene expression in the Apicomplexa.

Authors:  Mathieu Gissot; Kami Kim; Dick Schaap; James W Ajioka
Journal:  Int J Parasitol       Date:  2008-10-21       Impact factor: 3.981

Review 9.  Toxoplasma: the next 100years.

Authors:  Kami Kim; Louis M Weiss
Journal:  Microbes Infect       Date:  2008-07-10       Impact factor: 2.700

Review 10.  Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.

Authors:  Madalyn M McFarland; Sydney J Zach; Xiaofang Wang; Lakshmi-Prasad Potluri; Andrew J Neville; Jonathan L Vennerstrom; Paul H Davis
Journal:  Antimicrob Agents Chemother       Date:  2016-11-21       Impact factor: 5.191

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