Literature DB >> 18177014

Antiproliferative limonoids of a Malleastrum sp. from the Madagascar rainforest.

Brian T Murphy1, Peggie Brodie, Carla Slebodnick, James S Miller, Chris Birkinshaw, Lucien M Randrianjanaka, Rabodo Andriantsiferana, Vincent E Rasamison, Karen TenDyke, Edward M Suh, David G I Kingston.   

Abstract

Bioassay-guided fractionation of an ethanol extract of a Malleastrum sp. afforded three new limonoids, malleastrones A-C ( 1- 3), respectively. Each limonoid contained a rare tetranortriterpenoid skeleton. Structure elucidation of the isolates was carried out by analysis of one- and two-dimensional NMR and X-ray diffraction data. The novel isolates 1 and 2 were tested for antiproliferative activity against a panel of cancer cell lines and exhibited IC 50 values ranging from 0.19 to 0.63 microM.

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Year:  2008        PMID： 18177014      PMCID： PMC2908263          DOI： 10.1021/np070487q

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  5 in total

1.  Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.

Authors:  Shugeng Cao; Peggy J Brodie; James S Miller; Richard Randrianaivo; Fidy Ratovoson; Chris Birkinshaw; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  J Nat Prod       Date:  2007-02-27       Impact factor: 4.050

2.  Antiproliferative cardenolides of an Elaeodendron sp. from the Madagascar rain forest(1).

Authors:  Shugeng Cao; Peggy J Brodie; James S Miller; Fidy Ratovoson; Martin W Callmander; Sennen Randrianasolo; Etienne Rakotobe; Vincent E Rasamison; Edward M Suh; Karen TenDyke; David G I Kingston
Journal:  J Nat Prod       Date:  2007-06-05       Impact factor: 4.050

3.  Ipomoeassins A-E, cytotoxic macrocyclic glycoresins from the leaves of Ipomoea squamosa from the Suriname rainforest.

Authors:  Shugeng Cao; Rebecca C Guza; Jan H Wisse; James S Miller; Randy Evans; David G I Kingston
Journal:  J Nat Prod       Date:  2005-04       Impact factor: 4.050

4.  Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.

Authors:  Brian T Murphy; Shugeng Cao; Peggy J Brodie; James S Miller; Fidy Ratovoson; Chris Birkinshaw; Etienne Rakotobe; Vincent E Rasamison; Karen Tendyke; Edward M Suh; David G I Kingston
Journal:  Nat Prod Res       Date:  2008       Impact factor: 2.861

Review 5.  Limonoids: overview of significant bioactive triterpenes distributed in plants kingdom.

Authors:  Amit Roy; Shailendra Saraf
Journal:  Biol Pharm Bull       Date:  2006-02       Impact factor: 2.233
  5 in total
  9 in total

1.  Astrotricoumarin, an antiproliferative 4'-hydroxy-2',3'-dihydroprenylated methylcoumarin from an Astrotrichilia sp. from the Madagascar dry forest.

Authors:  Liva Harinantenaina; Peggy J Brodie; Martin W Callmander; Richard Randrianaivo; Stephan Rakotonandrasana; Vincent E Rasamison; Etienne Rakotobe; David G I Kingston
Journal:  Nat Prod Commun       Date:  2011-09       Impact factor: 0.986

2.  Antiproliferative compounds of Cyphostemma greveana from a Madagascar dry forest.

Authors:  Shugeng Cao; Yanpeng Hou; Peggy Brodie; James S Miller; Richard Randrianaivo; Etienne Rakotobe; Vincent E Rasamison; David G I Kingston
Journal:  Chem Biodivers       Date:  2011-04       Impact factor: 2.408

3.  Isolation of the New Antiplasmodial Butanolide, Malleastrumolide A, from Malleastrum sp. (Meliaceae) from Madagascar.

Authors:  Yongle Du; Alexander K Abedi; Ana Lisa Valenciano; Maria L Fernández-Murga; Maria B Cassera; Vincent E Rasamison; Wendy L Applequist; James S Miller; David G I Kingston
Journal:  Chem Biodivers       Date:  2017-12-15       Impact factor: 2.408

4.  Antiproliferative homoscalarane sesterterpenes from two Madagascan sponges.

Authors:  Liva Harinantenaina; Peggy J Brodie; Jean Maharavo; Gisele Bakary; Karen TenDyke; Yongchun Shen; David G I Kingston
Journal:  Bioorg Med Chem       Date:  2013-04-06       Impact factor: 3.641

5.  Antiproliferative compounds from Pongamiopsis pervilleana from the Madagascar Dry Forest.

Authors:  Liva Harinantenaina; Peggy J Brodie; Carla Slebodnick; Martin W Callmander; Etienne Rakotobe; Sennen Randrianasolo; Richard Randrianaivo; Vincent E Rasamison; Karen Tendyke; Yongchun Shen; Edward M Suh; David G I Kingston
Journal:  J Nat Prod       Date:  2010-09-24       Impact factor: 4.050

6.  Antiproliferative cassane diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar rainforest.

Authors:  Yanpeng Hou; Shugeng Cao; Peggy Brodie; James S Miller; Chris Birkinshaw; Fidisoa Ratovoson; Roland Rakotondrajaona; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  J Nat Prod       Date:  2007-12-29       Impact factor: 4.050

7.  Antiproliferative Diterpenes from a Malleastrum sp. from the Madagascar dry forest.

Authors:  Yixi Liu; C Houston Wiedle; Peggy J Brodie; Martin W Callmander; R Rakotondrajaona; Etienne Rakotobe; Vincent E Rasamison; David G I Kingston
Journal:  Nat Prod Commun       Date:  2015-09       Impact factor: 0.986

8.  Biodiversity conservation and drug discovery: Can they be combined? The Suriname and Madagascar experiences.

Authors:  Shugeng Cao; David G I Kingston
Journal:  Pharm Biol       Date:  2009-08-01       Impact factor: 3.503

9.  A natural love of natural products.

Authors:  David G I Kingston
Journal:  J Org Chem       Date:  2008-05-07       Impact factor: 4.354
  9 in total

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