BACKGROUND: It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited. OBJECTIVE: The objective of the study was to examine the association between legume and soy food consumption and self-reported type 2 DM. DESIGN: The study was conducted in a population-based prospective cohort of middle-aged Chinese women. We followed 64,227 women with no history of type 2 DM, cancer, or cardiovascular disease at study recruitment for an average of 4.6 y. Participants completed in-person interviews that collected information on diabetes risk factors, including dietary intake and physical activity in adulthood. Anthropometric measurements were taken. Dietary intake was assessed with a validated food-frequency questionnaire at the baseline survey and at the first follow-up survey administered 2-3 y after study recruitment. RESULTS: We observed an inverse association between quintiles of total legume intake and 3 mutually exclusive legume groups (peanuts, soybeans, and other legumes) and type 2 DM incidence. The multivariate-adjusted relative risk of type 2 DM for the upper quintile compared with the lower quintile was 0.62 (95% CI: 0.51, 0.74) for total legumes and 0.53 (95% CI: 0.45, 0.62) for soybeans. The association between soy products (other than soy milk) and soy protein consumption (protein derived from soy beans and their products) with type 2 DM was not significant. CONCLUSIONS: Consumption of legumes, soybeans in particular, was inversely associated with the risk type 2 DM.
BACKGROUND: It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited. OBJECTIVE: The objective of the study was to examine the association between legume and soy food consumption and self-reported type 2 DM. DESIGN: The study was conducted in a population-based prospective cohort of middle-aged Chinese women. We followed 64,227 women with no history of type 2 DM, cancer, or cardiovascular disease at study recruitment for an average of 4.6 y. Participants completed in-person interviews that collected information on diabetes risk factors, including dietary intake and physical activity in adulthood. Anthropometric measurements were taken. Dietary intake was assessed with a validated food-frequency questionnaire at the baseline survey and at the first follow-up survey administered 2-3 y after study recruitment. RESULTS: We observed an inverse association between quintiles of total legume intake and 3 mutually exclusive legume groups (peanuts, soybeans, and other legumes) and type 2 DM incidence. The multivariate-adjusted relative risk of type 2 DM for the upper quintile compared with the lower quintile was 0.62 (95% CI: 0.51, 0.74) for total legumes and 0.53 (95% CI: 0.45, 0.62) for soybeans. The association between soy products (other than soy milk) and soy protein consumption (protein derived from soy beans and their products) with type 2 DM was not significant. CONCLUSIONS: Consumption of legumes, soybeans in particular, was inversely associated with the risk type 2 DM.
Authors: C Heidemann; K Hoffmann; J Spranger; K Klipstein-Grobusch; M Möhlig; A F H Pfeiffer; H Boeing Journal: Diabetologia Date: 2005-05-12 Impact factor: 10.122
Authors: E J Feskens; S M Virtanen; L Räsänen; J Tuomilehto; J Stengård; J Pekkanen; A Nissinen; D Kromhout Journal: Diabetes Care Date: 1995-08 Impact factor: 19.112
Authors: D J Jenkins; T M Wolever; G Buckley; K Y Lam; S Giudici; J Kalmusky; A L Jenkins; R L Patten; J Bird; G S Wong Journal: Am J Clin Nutr Date: 1988-08 Impact factor: 7.045
Authors: G V Vahouny; I Adamson; W Chalcarz; S Satchithanandam; R Muesing; D M Klurfeld; S A Tepper; A Sanghvi; D Kritchevsky Journal: Atherosclerosis Date: 1985-08 Impact factor: 5.162
Authors: G Yang; X O Shu; F Jin; T Elasy; H L Li; Q Li; F Huang; X L Zhang; Y T Gao; W Zheng Journal: Eur J Clin Nutr Date: 2004-04 Impact factor: 4.016
Authors: Pablo Pérez-Martínez; Dimitri P Mikhailidis; Vasilios G Athyros; Mónica Bullo; Patrick Couture; María I Covas; Lawrence de Koning; Javier Delgado-Lista; Andrés Díaz-López; Christian A Drevon; Ramón Estruch; Katherine Esposito; Montserrat Fitó; Marta Garaulet; Dario Giugliano; Antonio García-Ríos; Niki Katsiki; Genovefa Kolovou; Benoît Lamarche; Maria Ida Maiorino; Guillermo Mena-Sánchez; Araceli Muñoz-Garach; Dragana Nikolic; José M Ordovás; Francisco Pérez-Jiménez; Manfredi Rizzo; Jordi Salas-Salvadó; Helmut Schröder; Francisco J Tinahones; Rafael de la Torre; Ben van Ommen; Suzan Wopereis; Emilio Ros; José López-Miranda Journal: Nutr Rev Date: 2017-05-01 Impact factor: 7.110
Authors: B Gillis; C Mobley; D D Stadler; J Hartstein; A Virus; S L Volpe; L El ghormli; M A Staten; J Bridgman; S McCormick Journal: Int J Obes (Lond) Date: 2009-08 Impact factor: 5.095
Authors: Ivonne Sluijs; Joline W J Beulens; Daphne L van der A; Annemieke M W Spijkerman; Diederick E Grobbee; Yvonne T van der Schouw Journal: Diabetes Care Date: 2009-10-13 Impact factor: 19.112