Literature DB >> 18155867

Cardiac cine MRI: comparison of 1.5 T, non-enhanced 3.0 T and blood pool enhanced 3.0 T imaging.

S C Gerretsen1, B Versluis, S C A M Bekkers, T Leiner.   

Abstract

INTRODUCTION: Cardiac cine imaging using balanced steady state free precession sequences (bSSFP) suffers from artefacts at 3.0 T. We compared bSSFP cardiac cine imaging at 1.5 T with gradient echo imaging at 3.0 T with and without a blood pool contrast agent.
MATERIALS AND METHODS: Eleven patients referred for cardiac cine imaging underwent imaging at 1.5 T and 3.0 T. At 3.0 T images were acquired before and after administration of 0.03 mmol/kg gadofosveset. Blood pool signal-to-noise ratio (SNR), temporal variations in SNR, ejection fraction and myocardial mass were compared. Subjective image quality was scored on a four-point scale.
RESULTS: Blood pool SNR increased with more than 75% at 3.0 T compared to 1.5 T (p<0.001); after contrast administration at 3.0 T SNR increased with 139% (p<0.001). However, variations in blood pool SNR at 3.0 T were nearly three times as high versus those at 1.5 T in the absence of contrast medium (p<0.001); after contrast administration this was reduced to approximately a factor 1.4 (p=0.21). Saturation artefacts led to significant overestimation of ejection fraction in the absence of contrast administration (1.5 T: 44.7+/-3.1 vs. 3.0 T: 50.7+/-4.2 [p=0.04] vs. 3.0 T post contrast: 43.4+/-2.9 [p=0.55]). Subjective image quality was highest for 1.5 T (2.8+/-0.3), and lowest for non-enhanced 3.0 T (1.7+/-0.6; p=0.006).
CONCLUSIONS: GRE cardiac cine imaging at 3.0 T after injection of the blood pool agent gadofosveset leads to improved objective and subjective cardiac cine image quality at 3.0 T and to the same conclusions regarding cardiac ejection fraction compared to bSSFP imaging at 1.5 T.

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Year:  2007        PMID: 18155867     DOI: 10.1016/j.ejrad.2007.11.004

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


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