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Literature DB >> 181534

Analysis of herpesvirus DNA substructure by means of restriction endonucleases.

Abstract

The mol. wt. and molar ratios of the Hind III and Hpa I fragments of HSV-1 DNA and the Eco RI fragments of HSV-2 DNA have been determined. Results obtained suggest that DNA isolated from both HSV-1 and HSV-2 consists of molecules with four different sequence arrangements which are present in similar amounts. Our explanation of the cleavage patterns of these four genome arrangements with the different restriction enzymes is presented. Some of the possible implications of these four genome arrangements for genetic recombination are discussed.

Entities: Disease Species

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Year: 1976 PMID： 181534 DOI： 10.1099/0022-1317-30-2-243

Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891

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Cited

25 in total

1. Orientation of herpes simplex virus type 1 immediate early mRNA's.

Authors: J B Clements; J McLauchlan; D J McGeoch
Journal: Nucleic Acids Res Date: 1979-09-11 Impact factor: 16.971

2. Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's.

Authors: R J Watson; C M Preston; J B Clements
Journal: J Virol Date: 1979-07 Impact factor: 5.103

3. Recombinants between herpes simplex virus types 1 and 2: analyses of genome structures and expression of immediate early polypeptides.

Authors: V G Preston; A J Davison; H S Marsden; M C Timbury; J H Subak-Sharpe; N M Wilkie
Journal: J Virol Date: 1978-11 Impact factor: 5.103

9. Anatomy of bovine mammillitis DNA. I Restriction endonuclease maps of four populations of molecules that differ in the relative orientation of their long and short components.

Authors: T G Buchman; B Roizman
Journal: J Virol Date: 1978-01 Impact factor: 5.103

10. Sequence arrangement in herpes simplex virus type 1 DNA: identification of terminal fragments in restriction endonuclease digests and evidence for inversions in redundant and unique sequences.

Authors: N M Wilkie; R Cortini
Journal: J Virol Date: 1976-10 Impact factor: 5.103

Analysis of herpesvirus DNA substructure by means of restriction endonucleases.

1. Orientation of herpes simplex virus type 1 immediate early mRNA's.

2. Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's.

3. Recombinants between herpes simplex virus types 1 and 2: analyses of genome structures and expression of immediate early polypeptides.

4. Structure of the joint region and the termini of the DNA of herpes simplex virus type 1.

5. Physical mapping of herpes simplex virus type 1 mutations by marker rescue.

6. Altered restriction endonuclease cleavage pattern of simian virus 40 DNA.

7. Inverted repetition in the chromosome of pseudorabies virus.

8. Physical map of the origin of defective DNA in herpes simplex virus type 1 DNA.

9. Anatomy of bovine mammillitis DNA. I Restriction endonuclease maps of four populations of molecules that differ in the relative orientation of their long and short components.

10. Sequence arrangement in herpes simplex virus type 1 DNA: identification of terminal fragments in restriction endonuclease digests and evidence for inversions in redundant and unique sequences.