Literature DB >> 1812368

Targeted relaxation enhancement agents for MRI.

R B Lauffer1.   

Abstract

The design, relative merits, and initial applications of targeted relaxation enhancement agents, a new form of MRI contrast media, are briefly discussed. These agents are designed to bind reversibly to target macromolecules in a tissue of interest, thus enhancing water proton relaxation efficiency and MRI contrast. Initial applications for targeted agents include blood pool and hepatobiliary imaging.

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Year:  1991        PMID： 1812368     DOI： 10.1002/mrm.1910220237

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  11 in total

1.  Strategies for the preparation of bifunctional gadolinium(III) chelators.

Authors:  Luca Frullano; Peter Caravan
Journal:  Curr Org Synth       Date:  2011-08-01       Impact factor: 1.975

2.  A model for MRI contrast enhancement using T1 agents.

Authors:  E T Ahrens; U Rothbächer; R E Jacobs; S E Fraser
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-21       Impact factor: 11.205

3.  Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging.

Authors:  Kevin Guo; Mikhail Y Berezin; Jie Zheng; Walter Akers; Franck Lin; Bao Teng; Olga Vasalatiy; Amir Gandjbakhche; Gary L Griffiths; Samuel Achilefu
Journal:  Chem Commun (Camb)       Date:  2010-04-13       Impact factor: 6.222

4.  In vivo magnetic resonance imaging of the estrogen receptor in an orthotopic model of human breast cancer.

Authors:  Adi Pais; Chidambaram Gunanathan; Raanan Margalit; Inbal Eti Biton; Ady Yosepovich; David Milstein; Hadassa Degani
Journal:  Cancer Res       Date:  2011-10-31       Impact factor: 12.701

Review 5.  MR imaging probes: design and applications.

Authors:  Eszter Boros; Eric M Gale; Peter Caravan
Journal:  Dalton Trans       Date:  2015-03-21       Impact factor: 4.390

6.  Immobilized contrast-enhanced MRI: Gadolinium-based long-term MR contrast enhancement of the vein graft vessel wall.

Authors:  Dimitris Mitsouras; Praveen Kumar Vemula; Peng Yu; Ming Tao; Binh T Nguyen; Christina M Campagna; Jeffrey M Karp; Robert V Mulkern; C Keith Ozaki; Frank J Rybicki
Journal:  Magn Reson Med       Date:  2011-01       Impact factor: 4.668

7.  High relaxivity magnetic resonance imaging contrast agents. Part 1. Impact of single donor atom substitution on relaxivity of serum albumin-bound gadolinium complexes.

Authors:  Stéphane Dumas; Vincent Jacques; Wei-Chuan Sun; Jeffrey S Troughton; Joel T Welch; Jaclyn M Chasse; Heribert Schmitt-Willich; Peter Caravan
Journal:  Invest Radiol       Date:  2010-10       Impact factor: 6.016

8.  High-relaxivity magnetic resonance imaging contrast agents. Part 2. Optimization of inner- and second-sphere relaxivity.

Authors:  Vincent Jacques; Stéphane Dumas; Wei-Chuan Sun; Jeffrey S Troughton; Matthew T Greenfield; Peter Caravan
Journal:  Invest Radiol       Date:  2010-10       Impact factor: 6.016

9.  Serum albumin targeted, pH-dependent magnetic resonance relaxation agents.

Authors:  Loïck Moriggi; Mohammad A Yaseen; Lothar Helm; Peter Caravan
Journal:  Chemistry       Date:  2012-02-10       Impact factor: 5.236

10.  Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium- and manganese-based T1 contrast agents.

Authors:  Peter Caravan; Christian T Farrar; Luca Frullano; Ritika Uppal
Journal:  Contrast Media Mol Imaging       Date:  2009 Mar-Apr       Impact factor: 3.161
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