Literature DB >> 18084306

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.

Joseph Lee1, James R Thompson, Maria Victoria Botuyan, Georges Mer.   

Abstract

The lysine demethylase JMJD2A has the unique property of binding trimethylated peptides from two different histone sequences (H3K4me3 and H4K20me3) through its tudor domains. Here we show using X-ray crystallography and calorimetry that H3K4me3 and H4K20me3, which are recognized with similar affinities by JMJD2A, adopt radically different binding modes, to the extent that we were able to design single point mutations in JMJD2A that inhibited the recognition of H3K4me3 but not H4K20me3 and vice versa.

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Year:  2007        PMID： 18084306      PMCID： PMC2211384          DOI： 10.1038/nsmb1326

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  17 in total

1.  Tudor, MBT and chromo domains gauge the degree of lysine methylation.

Authors:  Jeesun Kim; Jeremy Daniel; Alexsandra Espejo; Aimee Lake; Murli Krishna; Li Xia; Yi Zhang; Mark T Bedford
Journal:  EMBO Rep       Date:  2006-01-13       Impact factor: 8.807

2.  Double chromodomains cooperate to recognize the methylated histone H3 tail.

Authors:  John F Flanagan; Li-Zhi Mi; Maksymilian Chruszcz; Marcin Cymborowski; Katrina L Clines; Youngchang Kim; Wladek Minor; Fraydoon Rastinejad; Sepideh Khorasanizadeh
Journal:  Nature       Date:  2005-12-22       Impact factor: 49.962

3.  Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.

Authors:  Haitao Li; Serge Ilin; Wooikoon Wang; Elizabeth M Duncan; Joanna Wysocka; C David Allis; Dinshaw J Patel
Journal:  Nature       Date:  2006-05-21       Impact factor: 49.962

4.  Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.

Authors:  Pedro V Peña; Foteini Davrazou; Xiaobing Shi; Kay L Walter; Vladislav V Verkhusha; Or Gozani; Rui Zhao; Tatiana G Kutateladze
Journal:  Nature       Date:  2006-05-21       Impact factor: 49.962

5.  SMN tudor domain structure and its interaction with the Sm proteins.

Authors:  P Selenko; R Sprangers; G Stier; D Bühler; U Fischer; M Sattler
Journal:  Nat Struct Biol       Date:  2001-01

6.  Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Authors:  Johnathan R Whetstine; Amanda Nottke; Fei Lan; Maite Huarte; Sarit Smolikov; Zhongzhou Chen; Eric Spooner; En Li; Gongyi Zhang; Monica Colaiacovo; Yang Shi
Journal:  Cell       Date:  2006-04-06       Impact factor: 41.582

7.  Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A.

Authors:  Ying Huang; Jia Fang; Mark T Bedford; Yi Zhang; Rui-Ming Xu
Journal:  Science       Date:  2006-04-06       Impact factor: 47.728

8.  Structural insights into histone demethylation by JMJD2 family members.

Authors:  Zhongzhou Chen; Jianye Zang; Johnathan Whetstine; Xia Hong; Foteini Davrazou; Tatiana G Kutateladze; Michael Simpson; Qilong Mao; Cheol-Ho Pan; Shaodong Dai; James Hagman; Kirk Hansen; Yang Shi; Gongyi Zhang
Journal:  Cell       Date:  2006-05-04       Impact factor: 41.582

9.  Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.

Authors:  Steven A Jacobs; Sepideh Khorasanizadeh
Journal:  Science       Date:  2002-02-21       Impact factor: 47.728

10.  Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.

Authors:  Jean-François Couture; Evys Collazo; Patricia A Ortiz-Tello; Joseph S Brunzelle; Raymond C Trievel
Journal:  Nat Struct Mol Biol       Date:  2007-06-24       Impact factor: 15.369
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  107 in total

Review 1.  Keeping it in the family: diverse histone recognition by conserved structural folds.

Authors:  Kyoko L Yap; Ming-Ming Zhou
Journal:  Crit Rev Biochem Mol Biol       Date:  2010-10-06       Impact factor: 8.250

2.  Intra-chain 3D segment swapping spawns the evolution of new multidomain protein architectures.

Authors:  András Szilágyi; Yang Zhang; Péter Závodszky
Journal:  J Mol Biol       Date:  2011-11-04       Impact factor: 5.469

Review 3.  The PHD finger: a versatile epigenome reader.

Authors:  Roberto Sanchez; Ming-Ming Zhou
Journal:  Trends Biochem Sci       Date:  2011-04-21       Impact factor: 13.807

Review 4.  Structural insights into histone lysine demethylation.

Authors:  Haifeng Hou; Hongtao Yu
Journal:  Curr Opin Struct Biol       Date:  2010-10-21       Impact factor: 6.809

Review 5.  Molecular mechanisms and potential functions of histone demethylases.

Authors:  Susanne Marije Kooistra; Kristian Helin
Journal:  Nat Rev Mol Cell Biol       Date:  2012-04-04       Impact factor: 94.444

6.  Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.

Authors:  Weixiang Wang; Zhi Chen; Zhuo Mao; Huihui Zhang; Xiaojun Ding; She Chen; Xiaodong Zhang; Ruiming Xu; Bing Zhu
Journal:  EMBO Rep       Date:  2011-10-28       Impact factor: 8.807

7.  Structural cooperativity in histone H3 tail modifications.

Authors:  Deniz Sanli; Ozlem Keskin; Attila Gursoy; Burak Erman
Journal:  Protein Sci       Date:  2011-10-19       Impact factor: 6.725

Review 8.  Double-strand break repair: 53BP1 comes into focus.

Authors:  Stephanie Panier; Simon J Boulton
Journal:  Nat Rev Mol Cell Biol       Date:  2013-12-11       Impact factor: 94.444

9.  Profiling RE1/REST-mediated histone modifications in the human genome.

Authors:  Deyou Zheng; Keji Zhao; Mark F Mehler
Journal:  Genome Biol       Date:  2009-01-27       Impact factor: 13.583

10.  Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by Jumonji domain containing 1A (JMJD1A) homodimer.

Authors:  Satoshi Goda; Takayuki Isagawa; Yoko Chikaoka; Takeshi Kawamura; Hiroyuki Aburatani
Journal:  J Biol Chem       Date:  2013-11-08       Impact factor: 5.157
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