Literature DB >> 18071885

Contribution of the conserved A16Leu to insulin foldability.

Zhao-Jun Zhang1, Lan Wu, Zhi-Song Qiao, Ming-Qiang Qiao, You-Min Feng, Zhan-Yun Guo.   

Abstract

Contributions of the evolutionarily conserved A16Leu and B17Leu to insulin foldability were characterized by evaluating folding properties of single-chain insulin analogs. The results showed A16Leu had much more significant effects on the foldability of insulin than B17Leu.

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Year:  2008        PMID： 18071885     DOI： 10.1007/s10930-007-9124-x

Source DB:  PubMed          Journal:  Protein J        ISSN： 1572-3887            Impact factor:   2.371


  17 in total

1.  The insulin A and B chains contain sufficient structural information to form the native molecule.

Authors:  C C Wang; C L Tsou
Journal:  Trends Biochem Sci       Date:  1991-08       Impact factor: 13.807

2.  1H NMR spectrum of the native human insulin monomer. Evidence for conformational differences between the monomer and aggregated forms.

Authors:  M Roy; R W Lee; J Brange; M F Dunn
Journal:  J Biol Chem       Date:  1990-04-05       Impact factor: 5.157

3.  Principles that govern the folding of protein chains.

Authors:  C B Anfinsen
Journal:  Science       Date:  1973-07-20       Impact factor: 47.728

4.  The structure of 2Zn pig insulin crystals at 1.5 A resolution.

Authors:  E N Baker; T L Blundell; J F Cutfield; S M Cutfield; E J Dodson; G G Dodson; D M Hodgkin; R E Hubbard; N W Isaacs; C D Reynolds
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1988-07-06       Impact factor: 6.237

5.  The gapped duplex DNA approach to oligonucleotide-directed mutation construction.

Authors:  W Kramer; V Drutsa; H W Jansen; B Kramer; M Pflugfelder; H J Fritz
Journal:  Nucleic Acids Res       Date:  1984-12-21       Impact factor: 16.971

6.  Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability.

Authors:  Michael A Weiss; Satoe H Nakagawa; Wenhua Jia; Bin Xu; Qing-xin Hua; Ying-Chi Chu; Run-ying Wang; Panayotis G Katsoyannis
Journal:  Biochemistry       Date:  2002-01-22       Impact factor: 3.162

7.  Putative disulfide-forming pathway of porcine insulin precursor during its refolding in vitro.

Authors:  Z S Qiao; Z Y Guo; Y M Feng
Journal:  Biochemistry       Date:  2001-03-06       Impact factor: 3.162

8.  Effects of cysteine to serine substitutions in the two inter-chain disulfide bonds of insulin.

Authors:  Z Y Guo; Y M Feng
Journal:  Biol Chem       Date:  2001-03       Impact factor: 3.915

Review 9.  The in vitro oxidative folding of the insulin superfamily.

Authors:  Zhan-Yun Guo; Zhi-Song Qiao; You-Min Feng
Journal:  Antioxid Redox Signal       Date:  2008-01       Impact factor: 8.401

10.  Contribution of the absolutely conserved B8Gly to the foldability of insulin.

Authors:  Zhan-Yun Guo; Yue-Hua Tang; Shuai Wang; You-Min Feng
Journal:  Biol Chem       Date:  2003-05       Impact factor: 3.915
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  1 in total

1.  Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity.

Authors:  Ming Liu; Zhu-Li Wan; Ying-Chi Chu; Hassan Aladdin; Birgit Klaproth; Meredith Choquette; Qing-Xin Hua; Robert B Mackin; J Sunil Rao; Pierre De Meyts; Panayotis G Katsoyannis; Peter Arvan; Michael A Weiss
Journal:  J Biol Chem       Date:  2009-10-22       Impact factor: 5.157
  1 in total

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