Literature DB >> 18065222

Targeting RNA with cysteine-constrained peptides.

Virginia A Burns1, Benjamin G Bobay, Anne Basso, John Cavanagh, Christian Melander.   

Abstract

A combined approach for targeting RNA with novel, biologically active ligands has been developed using a cyclic peptide library and in silico modeling. This approach has successfully identified novel cyclic peptide constructs that can target bTAR RNA. Subsequently, RNA/peptide interactions were effectively modeled using the HADDOCK docking program.

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Year:  2007        PMID： 18065222      PMCID： PMC2277476          DOI： 10.1016/j.bmcl.2007.11.096

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  15 in total

1.  Experimental models of protein-RNA interaction: isolation and analyses of tRNA(Phe) and U1 snRNA-binding peptides from bacteriophage display libraries.

Authors:  P F Agris; M T Marchbank; W Newman; R Guenther; P Ingram; J Swallow; P Mucha; A Szyk; P Rekowski; E Peletskaya; S L Deutscher
Journal:  J Protein Chem       Date:  1999-05

2.  HADDOCK: a protein-protein docking approach based on biochemical or biophysical information.

Authors:  Cyril Dominguez; Rolf Boelens; Alexandre M J J Bonvin
Journal:  J Am Chem Soc       Date:  2003-02-19       Impact factor: 15.419

Review 3.  The human plasma proteome: history, character, and diagnostic prospects.

Authors:  N Leigh Anderson; Norman G Anderson
Journal:  Mol Cell Proteomics       Date:  2002-11       Impact factor: 5.911

Review 4.  Targeting RNA with small molecules.

Authors:  Yitzhak Tor
Journal:  Chembiochem       Date:  2003-10-06       Impact factor: 3.164

Review 5.  The cyclization of peptides and depsipeptides.

Authors:  John S Davies
Journal:  J Pept Sci       Date:  2003-08       Impact factor: 1.905

Review 6.  Chemical and functional diversity of small molecule ligands for RNA.

Authors:  Thomas Hermann
Journal:  Biopolymers       Date:  2003-09       Impact factor: 2.505

7.  Structural proteomics.

Authors:  Siân Renfrey; James Featherstone
Journal:  Nat Rev Drug Discov       Date:  2002-03       Impact factor: 84.694

8.  Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.

Authors:  P Mucha; A Szyk; P Rekowski; P A Weiss; P F Agris
Journal:  Biochemistry       Date:  2001-11-27       Impact factor: 3.162

9.  Design, synthesis, and biological activity of a cyclic peptide: an inhibitor of HIV-1 tat-TAR interactions in human cells.

Authors:  N Tamilarasu; I Huq; T M Rana
Journal:  Bioorg Med Chem Lett       Date:  2000-05-01       Impact factor: 2.823

10.  Design of a cyclic peptide that targets a viral RNA.

Authors:  Steven T Runyon; Joseph D Puglisi
Journal:  J Am Chem Soc       Date:  2003-12-24       Impact factor: 15.419
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  3 in total

1.  Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides.

Authors:  Kevin Day; John D Schneible; Ashlyn T Young; Vladimir A Pozdin; George Van Den Driessche; Lewis A Gaffney; Raphael Prodromou; Donald O Freytes; Denis Fourches; Michael Daniele; Stefano Menegatti
Journal:  J Mater Chem B       Date:  2020-08-26       Impact factor: 6.331

Review 2.  RNA-Binding Macrocyclic Peptides.

Authors:  Sunit Pal; Peter 't Hart
Journal:  Front Mol Biosci       Date:  2022-04-19

3.  Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.

Authors:  Amy Davidson; Krystyna Patora-Komisarska; John A Robinson; Gabriele Varani
Journal:  Nucleic Acids Res       Date:  2010-08-19       Impact factor: 16.971
  3 in total

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