| Literature DB >> 18031058 |
Sheng Yao1, Katherine J Schafer-Hales, Kevin D Belfield.
Abstract
Donor-pi-acceptor fluorene derivative 1c is a near-neutral pH indicator whose pKa of approximately 7.0 was determined by both absorption and fluorescence methods. 1c satisfies important criteria for a sensitive ratiomeric fluorescent pH indicator with a distinctive isoemissive point, good dispersion in cell cytosol, and low cytotoxicity. Furthermore, its 2PA cross section of 100 GM in its neutral form suggests its potential in two-photon fluorescence imaging applications.Entities:
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Year: 2007 PMID: 18031058 DOI: 10.1021/ol7026366
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005