PURPOSE: To estimate the incremental cost effectiveness of ICSI, and total costs for the population of Australia. METHODS: Treatment effects for three patient groups were drawn from a published systematic review and meta-analysis of trials comparing fertilisation outcomes for ICSI. Incremental costs derived from resource-based costing of ICSI and existing practice comparators for each patient group. RESULTS: Incremental cost per live birth for patients unsuited to IVF is estimated between A$8,500 and 13,400. For the subnormal semen indication, cost per live birth could be as low as A$3,600, but in the worst case scenario, there would just be additional incremental costs of A$600 per procedure. Multiplying out the additional costs of ICSI over the relevant target populations in Australia gives potential total financial implications of over A$31 million per annum. CONCLUSION: While there are additional benefits from ICSI procedure, particularly for those with subnormal sperm, the additional cost for the health care system is substantial.
PURPOSE: To estimate the incremental cost effectiveness of ICSI, and total costs for the population of Australia. METHODS: Treatment effects for three patient groups were drawn from a published systematic review and meta-analysis of trials comparing fertilisation outcomes for ICSI. Incremental costs derived from resource-based costing of ICSI and existing practice comparators for each patient group. RESULTS: Incremental cost per live birth for patients unsuited to IVF is estimated between A$8,500 and 13,400. For the subnormal semen indication, cost per live birth could be as low as A$3,600, but in the worst case scenario, there would just be additional incremental costs of A$600 per procedure. Multiplying out the additional costs of ICSI over the relevant target populations in Australia gives potential total financial implications of over A$31 million per annum. CONCLUSION: While there are additional benefits from ICSI procedure, particularly for those with subnormal sperm, the additional cost for the health care system is substantial.
Authors: A E Alfonsín; A R Amato; A Arrighi; J A Blaquier; M Cogorno; E S Feldman; F Gonzalez Echeverría; M Horton; D L Della Vecchia; N Millas Journal: Fertil Steril Date: 1998-03 Impact factor: 7.329
Authors: Francesco Del Giudice; Federico Belladelli; Tony Chen; Frank Glover; Evan A Mulloy; Alex M Kasman; Alessandro Sciarra; Stefano Salciccia; Vittorio Canale; Martina Maggi; Matteo Ferro; Gian Maria Busetto; Ettore De Berardinis; Andrea Salonia; Michael L Eisenberg Journal: Andrologia Date: 2022-03-03 Impact factor: 2.532