Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Synthesis of benzoxazinone derivatives: a new route to 2 (N phthaloylmethyl)-4H-3,1-benzoxazin-4-one.

Literature DB >> 18007471

Synthesis of benzoxazinone derivatives: a new route to 2 (N phthaloylmethyl)-4H-3,1-benzoxazin-4-one.

Abstract

A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.

Entities: Chemical

Mesh：

Substances：

Year: 2004 PMID： 18007471 PMCID： PMC6147371 DOI： 10.3390/90800705

Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411

1 in total

1. Synthesis and central nervous system activity of quinazolones related to 2-methyl-3-(o-tolyl)-4(3H)-quinazolone (methaqualone).

Authors: I R Ager; D R Harrison; P D Kennewell; J B Taylor
Journal: J Med Chem Date: 1977-03 Impact factor: 7.446

1 in total

7 in total

1. 2-(4-Amino-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-ylmeth-yl)isoindoline-1,3-dione.

Authors: Uzma Yunus; Mohammad Kalim Tahir; Moazzam Hussain Bhatti; Naveeda Yousaf; Madeleine Helliwell
Journal: Acta Crystallogr Sect E Struct Rep Online Date: 2008-01-23

2. The 1:1 adduct of caffeine and 2-(1,3-dioxoisoindolin-2-yl)acetic acid.

Authors: Moazzam H Bhatti; Uzma Yunus; Sohail Saeed; Syed Raza Shah; Wing-Tak Wong
Journal: Acta Crystallogr Sect E Struct Rep Online Date: 2011-08-02

3. Microwave assisted synthesis of 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives using the complex cyanuric chloride/N,N-dimethylformamide.

Authors: Mehdi Shariat; Mohd Wahid Samsudin; Zuriati Zakaria
Journal: Molecules Date: 2012-09-28 Impact factor: 4.411

4. Facile synthesis and herbicidal evaluation of 4H-3,1-benzoxazin-4-ones and 3H-quinazolin-4-ones with 2-phenoxymethyl substituents.

Authors: Zumuretiguli Aibibuli; Yufeng Wang; Haiyang Tu; Xiaoting Huang; Aidong Zhang
Journal: Molecules Date: 2012-03-14 Impact factor: 4.411

Synthesis of benzoxazinone derivatives: a new route to 2 (N phthaloylmethyl)-4H-3,1-benzoxazin-4-one.

1. Synthesis and central nervous system activity of quinazolones related to 2-methyl-3-(o-tolyl)-4(3H)-quinazolone (methaqualone).

1. 2-(4-Amino-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-ylmeth-yl)isoindoline-1,3-dione.

2. The 1:1 adduct of caffeine and 2-(1,3-dioxoisoindolin-2-yl)acetic acid.

3. Microwave assisted synthesis of 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives using the complex cyanuric chloride/N,N-dimethylformamide.

4. Facile synthesis and herbicidal evaluation of 4H-3,1-benzoxazin-4-ones and 3H-quinazolin-4-ones with 2-phenoxymethyl substituents.

5. Forecast of Phase Diagram for the Synthesis of a Complex for the Detection of Cr⁶⁺ Ions.

6. Methyl 2-(3-chloro-benzamido)-benzoate.

7. Design and syntheses of 7-nitro-2-aryl-4H-benzo[d][1,3]oxazin-4-ones as potent anticancer and antioxidant agents.