Literature DB >> 17984764

Multiple-electrode radiofrequency ablation of in vivo porcine liver: comparative studies of consecutive monopolar, switching monopolar versus multipolar modes.

Jeong Min Lee1, Joon Koo Han, Hyo Cheol Kim, Se Hyung Kim, Kyung Won Kim, Seung Moon Joo, Byung Ihn Choi.   

Abstract

PURPOSE: To evaluate the in vivo efficiency of 2 multiple-electrode radiofrequency (RF) systems to create confluent areas of coagulation in porcine liver, compared with consecutive overlapping ablation.
MATERIALS AND METHODS: A total of 18 coagulations were created with 3 RF devices and 3 internally cooled electrodes at laparotomy in 6 female pigs. RF was applied to the porcine livers in a consecutive, monopolar mode (group A), in a switching monopolar mode (group B), or in a multipolar mode (group C). Energy efficiency values for the RF systems, shape and dimensions, and the coefficients of variation of the coagulation zones were compared in the 3 groups.
RESULTS: The duration of the RF ablation procedures in groups A, B, and C were 36 minutes, 18 minutes, and 21.2 +/- 1.9 minutes. The average energy delivered to produce 1 cm(3) coagulation was greater in group A (5.6 +/- 2.3 kJ/cm(3)) than in group B (1.8 +/- 0.5 kJ/cm(3)) or in group C (2.0 +/- 0.8 kJ/cm(3)) (P < 0.05). The mean volumes of the coagulations in groups A, B, and C were 28.8 +/- 13.2 cm(3) in group A, 49.1 +/- 12.3 cm(3) in group B, and 40.6 +/- 16.3 cm(3) in group C, respectively (P = 0.07). Regarding the shape of the coagulations, the coagulations of groups B (isoperimetric ratio; 0.88) and C (0.84) were more spherical than those of group A (0.69) (P < 0.05). In addition, the coefficients of variation of the volumes of the ablation zones in groups A, B, and C were 0.46, 0.25, and 0.40, respectively.
CONCLUSIONS: Multiple-electrode RF systems in switching monopolar and multipolar modes more efficiently created a larger, confluent, spherical-shaped coagulation than conventional consecutive RF ablation.

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Year:  2007        PMID: 17984764     DOI: 10.1097/RLI.0b013e3180661aad

Source DB:  PubMed          Journal:  Invest Radiol        ISSN: 0020-9996            Impact factor:   6.016


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