Literature DB >> 26034376

Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option.

Guilherme Lopes P Martins1, Joao Paulo G Bernardes1, Marcello S Rovella1, Raphael G Andrade1, Publio Cesar C Viana1, Paulo Herman1, Giovanni Guido Cerri1, Marcos Roberto Menezes1.   

Abstract

We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation (RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism.

Entities:  

Keywords:  Hypersplenism; Percutaneous radiofrequency ablation; Portal hypertension; Splenic ablation; Thrombocytopenia

Mesh:

Substances:

Year:  2015        PMID: 26034376      PMCID: PMC4445118          DOI: 10.3748/wjg.v21.i20.6391

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  49 in total

Review 1.  Schistosomiasis.

Authors:  Allen G P Ross; Paul B Bartley; Adrian C Sleigh; G Richard Olds; Yuesheng Li; Gail M Williams; Donald P McManus
Journal:  N Engl J Med       Date:  2002-04-18       Impact factor: 91.245

2.  CT-guided percutaneous radiofrequency ablation of spleen: a preliminary study.

Authors:  Toshiyuki Matsuoka; Akira Yamamoto; Tomohisa Okuma; Yoshimasa Oyama; Kenji Nakamura; Yuichi Inoue
Journal:  AJR Am J Roentgenol       Date:  2007-04       Impact factor: 3.959

3.  Randomized clinical trial of splenic radiofrequency ablation versus splenectomy for severe hypersplenism.

Authors:  K Feng; K Ma; Q Liu; Q Wu; J Dong; P Bie
Journal:  Br J Surg       Date:  2010-12-24       Impact factor: 6.939

Review 4.  Splenomegaly, hypersplenism and coagulation abnormalities in liver disease.

Authors:  P A McCormick; K M Murphy
Journal:  Baillieres Best Pract Res Clin Gastroenterol       Date:  2000-12

5.  Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial.

Authors:  J Michael Henderson; Thomas D Boyer; Michael H Kutner; John R Galloway; Layton F Rikkers; Lennox J Jeffers; Kareem Abu-Elmagd; Jason Connor
Journal:  Gastroenterology       Date:  2006-05       Impact factor: 22.682

6.  Partial splenic embolization in patients with cirrhosis: efficacy, tolerance and long-term outcome in 32 patients.

Authors:  Gisèle N'Kontchou; Olivier Seror; Valérie Bourcier; Djamila Mohand; Yves Ajavon; Laurent Castera; Véronique Grando-Lemaire; Nathalie Ganne-Carrie; Nicolas Sellier; Jean-Claude Trinchet; Michel Beaugrand
Journal:  Eur J Gastroenterol Hepatol       Date:  2005-02       Impact factor: 2.566

7.  Partial splenic embolization versus splenectomy for the management of hypersplenism in cirrhotic patients.

Authors:  Mahmoud A Amin; Mohamed M el-Gendy; Ibrahim E Dawoud; Ashraf Shoma; Ahmed M Negm; Talal A Amer
Journal:  World J Surg       Date:  2009-08       Impact factor: 3.352

8.  The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlations.

Authors:  D Tripathi; G Therapondos; E Jackson; D N Redhead; P C Hayes
Journal:  Gut       Date:  2002-08       Impact factor: 23.059

9.  Large liver tumors: protocol for radiofrequency ablation and its clinical application in 110 patients--mathematic model, overlapping mode, and electrode placement process.

Authors:  Min-Hua Chen; Wei Yang; Kun Yan; Ming-Wu Zou; Luigi Solbiati; Ji-Bin Liu; Ying Dai
Journal:  Radiology       Date:  2004-05-27       Impact factor: 11.105

10.  Relationship between splenomegaly and hematologic findings in patients with hepatosplenic schistosomiasis.

Authors:  Luiz Arthur Calheiros Leite; Ana Lúcia Coutinho Domingues; Edmundo Pessoa Lopes; Rita de Cássia Dos Santos Ferreira; Adenor de Almeida Pimenta; Caíque Silveira Martins da Fonseca; Bianka Santana Dos Santos; Vera Lúcia de Menezes Lima
Journal:  Rev Bras Hematol Hemoter       Date:  2013
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  1 in total

1.  Microwave Ablation for the Treatment of Hypersplenism: Short Waves, Low Cost, Big Results.

Authors:  Jonathan Ha; Mack Hendrix; Adam G Guyer
Journal:  Dig Dis Sci       Date:  2016-01       Impact factor: 3.199

  1 in total

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