Literature DB >> 17981580

Classification algorithms for phenotype prediction in genomics and proteomics.

Habtom W Ressom1, Rency S Varghese, Zhen Zhang, Jianhua Xuan, Robert Clarke.   

Abstract

This paper gives an overview of statistical and machine learning-based feature selection and pattern classification algorithms and their application in molecular cancer classification or phenotype prediction. In particular, the paper focuses on the use of these computational methods for gene and peak selection from microarray and mass spectrometry data, respectively. The selected features are presented to a classifier for phenotype prediction.

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Year:  2008        PMID: 17981580      PMCID: PMC2204040          DOI: 10.2741/2712

Source DB:  PubMed          Journal:  Front Biosci        ISSN: 1093-4715


  51 in total

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Review 6.  Proteomic cancer classification with mass spectrometry data.

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8.  Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer.

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10.  Diagnosis of Ovarian Cancer Using Decision Tree Classification of Mass Spectral Data.

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  13 in total

Review 1.  The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.

Authors:  Robert Clarke; Habtom W Ressom; Antai Wang; Jianhua Xuan; Minetta C Liu; Edmund A Gehan; Yue Wang
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2.  Reconstruct modular phenotype-specific gene networks by knowledge-driven matrix factorization.

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Journal:  Bioinformatics       Date:  2009-06-19       Impact factor: 6.937

3.  Identifying radiation exposure biomarkers from mouse blood transcriptome.

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Review 4.  Genomics and bioinformatics of Parkinson's disease.

Authors:  Sonja W Scholz; Tim Mhyre; Habtom Ressom; Salim Shah; Howard J Federoff
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Review 5.  Practical issues in building risk-predicting models for complex diseases.

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6.  Signal processing for metagenomics: extracting information from the soup.

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7.  SWISS MADE: Standardized WithIn Class Sum of Squares to evaluate methodologies and dataset elements.

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Journal:  PLoS One       Date:  2010-03-26       Impact factor: 3.240

8.  Strategy to find molecular signatures in a small series of rare cancers: validation for radiation-induced breast and thyroid tumors.

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9.  A support vector machine model provides an accurate transcript-level-based diagnostic for major depressive disorder.

Authors:  J S Yu; A Y Xue; E E Redei; N Bagheri
Journal:  Transl Psychiatry       Date:  2016-10-25       Impact factor: 6.222

10.  Availability of MudPIT data for classification of biological samples.

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