Literature DB >> 17974125

An introduction to metabolomics and its potential application in veterinary science.

Oliver A H Jones1, Victoria L Cheung.   

Abstract

Metabolomics has been found to be applicable to a wide range of fields, including the study of gene function, toxicology, plant sciences, environmental analysis, clinical diagnostics, nutrition, and the discrimination of organism genotypes. This approach combines high-throughput sample analysis with computer-assisted multivariate pattern-recognition techniques. It is increasingly being deployed in toxico- and pharmacokinetic studies in the pharmaceutical industry, especially during the safety assessment of candidate drugs in human medicine. However, despite the potential of this technique to reduce both costs and the numbers of animals used for research, examples of the application of metabolomics in veterinary research are, thus far, rare. Here we give an introduction to metabolomics and discuss its potential in the field of veterinary science.

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Year:  2007        PMID: 17974125

Source DB:  PubMed          Journal:  Comp Med        ISSN: 1532-0820            Impact factor:   0.982


  10 in total

Review 1.  Metabolomics in the study of spontaneous animal diseases.

Authors:  Helena Tran; Malcolm McConville; Panayiotis Loukopoulos
Journal:  J Vet Diagn Invest       Date:  2020-08-18       Impact factor: 1.279

2.  Biochemical Effects of Routine Gonadectomy on Blood of Domestic Ferrets (Mustela putorius furo).

Authors:  Michelle C Whitehead; Olivia A Petritz; Mary Doerr; Michael K Stoskopf; Tara M Harrison
Journal:  J Am Assoc Lab Anim Sci       Date:  2020-06-25       Impact factor: 1.232

Review 3.  Current and Future Perspectives on the Structural Identification of Small Molecules in Biological Systems.

Authors:  Daniel A Dias; Oliver A H Jones; David J Beale; Berin A Boughton; Devin Benheim; Konstantinos A Kouremenos; Jean-Luc Wolfender; David S Wishart
Journal:  Metabolites       Date:  2016-12-15

Review 4.  A Review of Analytical Techniques and Their Application in Disease Diagnosis in Breathomics and Salivaomics Research.

Authors:  David J Beale; Oliver A H Jones; Avinash V Karpe; Saravanan Dayalan; Ding Yuan Oh; Konstantinos A Kouremenos; Warish Ahmed; Enzo A Palombo
Journal:  Int J Mol Sci       Date:  2016-12-23       Impact factor: 5.923

5.  Chytridiomycosis causes catastrophic organism-wide metabolic dysregulation including profound failure of cellular energy pathways.

Authors:  Laura F Grogan; Lee F Skerratt; Lee Berger; Scott D Cashins; Robert D Trengove; Joel P A Gummer
Journal:  Sci Rep       Date:  2018-05-29       Impact factor: 4.379

6.  Respiratory metabolites in bronchoalveolar lavage fluid (BALF) and exhaled breath condensate (EBC) can differentiate horses affected by severe equine asthma from healthy horses.

Authors:  Marilena Bazzano; Luca Laghi; Chenglin Zhu; Gian Enrico Magi; Beniamino Tesei; Fulvio Laus
Journal:  BMC Vet Res       Date:  2020-07-08       Impact factor: 2.741

7.  Senecavirus A- and Non-Infected Cells at Early Stage of Infection: Comparative Metabolomic Profiles.

Authors:  Fuxiao Liu; Bo Ni; Rong Wei
Journal:  Front Cell Infect Microbiol       Date:  2022-01-07       Impact factor: 5.293

8.  Differences in the serum metabolome profile of dairy cows according to the BHB concentration revealed by proton nuclear magnetic resonance spectroscopy (1H-NMR).

Authors:  Anastasia Lisuzzo; Luca Laghi; Vanessa Faillace; Chenglin Zhu; Barbara Contiero; Massimo Morgante; Elisa Mazzotta; Matteo Gianesella; Enrico Fiore
Journal:  Sci Rep       Date:  2022-02-15       Impact factor: 4.379

9.  Future Veterinary Diagnostics.

Authors:  Bob Dahlhausen
Journal:  J Exot Pet Med       Date:  2010-09-19       Impact factor: 0.453

10.  Metabolomics Analysis of the Deterioration Mechanism and Storage Time Limit of Tender Coconut Water during Storage.

Authors:  Yunwu Zhang; Wenxue Chen; Haiming Chen; Qiuping Zhong; Yonghuan Yun; Weijun Chen
Journal:  Foods       Date:  2020-01-03
  10 in total

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