Literature DB >> 17971752

Synthesis and natural distribution of anti-inflammatory alkamides from Echinacea.

George A Kraus1, Jaehoon Bae, Lankun Wu, Eve Wurtele.   

Abstract

The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17971752      PMCID: PMC2065760          DOI: 10.3390/11100758

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.411


  13 in total

1.  Alkamide levels in Echinacea purpurea: effects of processing, drying and storage.

Authors:  N B Perry; J W van Klink; E J Burgess; G A Parmenter
Journal:  Planta Med       Date:  2000-02       Impact factor: 3.352

2.  Synthesis of a physiologically active compound of the pellitorine structure.

Authors:  L CROMBIE; S H HARPER
Journal:  Nature       Date:  1949-12-17       Impact factor: 49.962

3.  Light-mediated antifungal activity of Echinacea extracts.

Authors:  S E Binns; B Purgina; C Bergeron; M L Smith; L Ball; B R Baum; J T Arnason
Journal:  Planta Med       Date:  2000-04       Impact factor: 3.352

4.  An evaluation of Echinacea angustifolia in experimental rhinovirus infections.

Authors:  Ronald B Turner; Rudolf Bauer; Karin Woelkart; Thomas C Hulsey; J David Gangemi
Journal:  N Engl J Med       Date:  2005-07-28       Impact factor: 91.245

5.  Macrophage activating effects of new alkamides from the roots of Echinacea species.

Authors:  Ying Chen; Tong Fu; Tao Tao; Jinghua Yang; Yung Chang; Meihua Wang; Linda Kim; Luping Qu; John Cassady; Ric Scalzo; Xiping Wang
Journal:  J Nat Prod       Date:  2005-05       Impact factor: 4.050

6.  Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal rats.

Authors:  Vinti Goel; Chuck Chang; Jan V Slama; Richard Barton; Rudolf Bauer; Roland Gahler; Tapan K Basu
Journal:  Int Immunopharmacol       Date:  2002-02       Impact factor: 4.932

7.  Patterns of Variation in Alkamides and Cichoric Acid in Roots and Aboveground Parts of Echinacea purpurea (L.) Moench.

Authors:  Luping Qu; Ying Chen; Xiping Wang; Richard Scalzo; Jeanine M Davis
Journal:  HortScience       Date:  2005-08       Impact factor: 1.455

8.  TLC and HPLC Analysis of Alkamides in Echinacea Drugs1,2.

Authors:  R Bauer; P Remiger
Journal:  Planta Med       Date:  1989-08       Impact factor: 3.352

Review 9.  Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties.

Authors:  Joanne Barnes; Linda A Anderson; Simon Gibbons; J David Phillipson
Journal:  J Pharm Pharmacol       Date:  2005-08       Impact factor: 3.765

10.  In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species.

Authors:  B Müller-Jakic; W Breu; A Pröbstle; K Redl; H Greger; R Bauer
Journal:  Planta Med       Date:  1994-02       Impact factor: 3.352

View more
  4 in total

1.  Alkamide stability in Echinacea purpurea extracts with and without phenolic acids in dry films and in solution.

Authors:  Yi Liu; Patricia A Murphy
Journal:  J Agric Food Chem       Date:  2007-01-10       Impact factor: 5.279

2.  Effects of chemically characterized fractions from aerial parts of Echinacea purpurea and E. angustifolia on myelopoiesis in rats.

Authors:  Sindhura Ramasahayam; Hany N Baraka; Fatma M Abdel Bar; Bilal S Abuasal; Mark P Widrlechner; Khalid A El Sayed; Sharon A Meyer
Journal:  Planta Med       Date:  2011-08-25       Impact factor: 3.352

3.  Metabolic profiling of echinacea genotypes and a test of alternative taxonomic treatments.

Authors:  Lankun Wu; Philip M Dixon; Basil J Nikolau; George A Kraus; Mark P Widrlechner; Eve Syrkin Wurtele
Journal:  Planta Med       Date:  2008-12-19       Impact factor: 3.352

4.  The application of multiplex fluorimetric sensor for the analysis of flavonoids content in the medicinal herbs family Asteraceae, Lamiaceae, Rosaceae.

Authors:  Oksana Sytar; Klaudia Bruckova; Elena Hunkova; Marek Zivcak; Kiessoun Konate; Marian Brestic
Journal:  Biol Res       Date:  2015-01-16       Impact factor: 5.612

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.