Literature DB >> 8134414

In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species.

B Müller-Jakic1, W Breu, A Pröbstle, K Redl, H Greger, R Bauer.   

Abstract

Polyunsaturated alkamides isolated from Achillea species, Echinacea angustifolia DC., Anacyclus pyrethrum (L.) Link, and Aaronsohnia pubescens (Desf.) Bremer & Humphries, (Compositae) were shown to possess inhibitory activity in in vitro cyclooxygenase (sheep seminal microsomes) and 5-lipoxygenase (porcine leukocytes) assays. Activity appeared to depend on the particular structure of the alkamides.

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Year:  1994        PMID： 8134414     DOI： 10.1055/s-2006-959404

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  14 in total

1.  Metabolomic analysis reveals that the accumulation of specific secondary metabolites in Echinacea angustifolia cells cultured in vitro can be controlled by light.

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2.  Enrichment of Echinacea angustifolia with Bauer alkylamide 11 and Bauer ketone 23 increased anti-inflammatory potential through interference with cox-2 enzyme activity.

Authors:  Carlie A Lalone; Nan Huang; Ludmila Rizshsky; Man-Yu Yum; Navrozedeep Singh; Cathy Hauck; Basil J Nikolau; Eve S Wurtele; Marian L Kohut; Patricia A Murphy; Diane F Birt
Journal:  J Agric Food Chem       Date:  2010-08-11       Impact factor: 5.279

3.  Evaluation of immunopathologic effects of aqueous extract of Echinacea purpurea in mice after experimental challenge with Pasteurella multocida serotype A.

Authors:  A Rezaie; D Gharibi; M Ghorbanpoor; S Anbari; M Pourmahdi Broojeni
Journal:  Iran J Vet Res       Date:  2014       Impact factor: 1.376

Review 4.  A review on the management of migraine in the Avicenna's Canon of Medicine.

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Review 5.  Echinacea for preventing and treating the common cold.

Authors:  Marlies Karsch-Völk; Bruce Barrett; David Kiefer; Rudolf Bauer; Karin Ardjomand-Woelkart; Klaus Linde
Journal:  Cochrane Database Syst Rev       Date:  2014-02-20

6.  Synthesis and natural distribution of anti-inflammatory alkamides from Echinacea.

Authors:  George A Kraus; Jaehoon Bae; Lankun Wu; Eve Wurtele
Journal:  Molecules       Date:  2006-10-18       Impact factor: 4.411

7.  Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine.

Authors:  Birgit Waltenberger; Daniela Schuster; Sompol Paramapojn; Wandee Gritsanapan; Gerhard Wolber; Judith M Rollinger; Hermann Stuppner
Journal:  Phytomedicine       Date:  2010-09-20       Impact factor: 5.340

8.  Echinacea: a miracle herb against aging and cancer? Evidence in vivo in mice.

Authors:  Sandra C Miller
Journal:  Evid Based Complement Alternat Med       Date:  2005-09       Impact factor: 2.629

Review 9.  Echinacea purpurea: Pharmacology, phytochemistry and analysis methods.

Authors:  Azadeh Manayi; Mahdi Vazirian; Soodabeh Saeidnia
Journal:  Pharmacogn Rev       Date:  2015 Jan-Jun

10.  Plant-endophytes interaction influences the secondary metabolism in Echinacea purpurea (L.) Moench: an in vitro model.

Authors:  Valentina Maggini; Marinella De Leo; Alessio Mengoni; Eugenia Rosaria Gallo; Elisangela Miceli; Rose Vanessa Bandeira Reidel; Sauro Biffi; Luisa Pistelli; Renato Fani; Fabio Firenzuoli; Patrizia Bogani
Journal:  Sci Rep       Date:  2017-12-05       Impact factor: 4.379
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