AIM: To evaluate performance of the Ages and Stages Questionnaires (full ASQ), and a shortened version (short ASQ), in detecting children with severe neurosensory disability in the Magpie Trial follow-up study. METHODS: All children, born to women in the Magpie Trial and selected for follow-up, with a completed full 30 items and/or short 9-items ASQ were included in this analysis. Sensitivity and specificity, corrected for verification bias, were computed to assess detection ability. RESULTS: Of the 2046 children who completed a full ASQ, 406 (19.8%) failed the assessment, 54 of whom had confirmed neurosensory disability. Adjusted sensitivity and specificity (95% confidence intervals) were 87.4% (62.9-96.6%), and 82.3% (80.5-83.9%), respectively. Two of the five domains in the full ASQ (Fine Motor and Problem Solving) contributed little to detection ability. Sensitivity and specificity for the short ASQ were 69.2% and 95.7%, respectively. CONCLUSIONS: Sensitivity of the full ASQ for severe neurosensory disability is generally good, and does not appear to be much reduced by restricting questions to three out of the five domains. The short ASQ reported here reduced performance, although this might be improved by a different choice of questions or scoring system.
AIM: To evaluate performance of the Ages and Stages Questionnaires (full ASQ), and a shortened version (short ASQ), in detecting children with severe neurosensory disability in the Magpie Trial follow-up study. METHODS: All children, born to women in the Magpie Trial and selected for follow-up, with a completed full 30 items and/or short 9-items ASQ were included in this analysis. Sensitivity and specificity, corrected for verification bias, were computed to assess detection ability. RESULTS: Of the 2046 children who completed a full ASQ, 406 (19.8%) failed the assessment, 54 of whom had confirmed neurosensory disability. Adjusted sensitivity and specificity (95% confidence intervals) were 87.4% (62.9-96.6%), and 82.3% (80.5-83.9%), respectively. Two of the five domains in the full ASQ (Fine Motor and Problem Solving) contributed little to detection ability. Sensitivity and specificity for the short ASQ were 69.2% and 95.7%, respectively. CONCLUSIONS: Sensitivity of the full ASQ for severe neurosensory disability is generally good, and does not appear to be much reduced by restricting questions to three out of the five domains. The short ASQ reported here reduced performance, although this might be improved by a different choice of questions or scoring system.
Authors: Nathalie L Maitre; Gena Henderson; Shirley Gogliotti; Jennifer Pearson; Ashley Simmons; Lu Wang; James C Slaughter; Alexandra P Key Journal: J Clin Exp Neuropsychol Date: 2014-06-23 Impact factor: 2.475
Authors: Maia M Noeder; Beth A Logan; Kari L Struemph; Nancy Condon; Isabel Mueller; Barbara Sands; Ryan R Davies; Erica Sood Journal: Cardiol Young Date: 2017-04-05 Impact factor: 1.093
Authors: Elizabeth L Turner; Siham Sikander; Omer Bangash; Ahmed Zaidi; Lisa Bates; John Gallis; Nima Ganga; Karen O'Donnell; Atif Rahman; Joanna Maselko Journal: Trials Date: 2016-09-08 Impact factor: 2.279
Authors: Catherine M Kirk; Jean Claude Uwamungu; Kim Wilson; Bethany L Hedt-Gauthier; Neo Tapela; Peter Niyigena; Christian Rusangwa; Merab Nyishime; Evrard Nahimana; Fulgence Nkikabahizi; Christine Mutaganzwa; Eric Ngabireyimana; Francis Mutabazi; Hema Magge Journal: BMC Pediatr Date: 2017-11-15 Impact factor: 2.125