| Literature DB >> 17962029 |
Clemens Lamberth1, Andre Jeanguenat, Fredrik Cederbaum, Alain De Mesmaeker, Martin Zeller, Hans-Joachim Kempf, Ronald Zeun.
Abstract
Isocyanide-based multicomponent reactions of the Ugi- and Passerini-type have been valuable tools for the rapid exploration of the novel fungicidal compound classes of phenylglycinamides and mandelamides. Mandipropamid (6), which was discovered during this derivatisation, displays excellent activity against the economically important phytopathogens Phytophthora infestans (potato and tomato late blight) and Plasmopara viticola (grape downy mildew).Entities:
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Year: 2007 PMID： 17962029 DOI： 10.1016/j.bmc.2007.10.019
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641