BACKGROUND: Large oral lesions comprise the risk that an incisional biopsy does not reveal the most aggressive site in spite of carefully selecting the place of biopsy. CASE REPORT: The first incisional biopsy of a large, clinically suspect, oral lesion could not identify the subepidermal spread of a recurrent oral squamous cell carcinoma. Atypical cells obtained by a simultaneous brush biopsy prompted a renewed, incisional biopsy which finally established the diagnosis of a recurrent, oral squamous cell carcinoma. CONCLUSIONS: The presented case emphasizes the value of brush biopsy in the follow-up of oral squamous cell carcinoma, especially in examination of oral lesions covering a large area.
BACKGROUND: Large oral lesions comprise the risk that an incisional biopsy does not reveal the most aggressive site in spite of carefully selecting the place of biopsy. CASE REPORT: The first incisional biopsy of a large, clinically suspect, oral lesion could not identify the subepidermal spread of a recurrent oral squamous cell carcinoma. Atypical cells obtained by a simultaneous brush biopsy prompted a renewed, incisional biopsy which finally established the diagnosis of a recurrent, oral squamous cell carcinoma. CONCLUSIONS: The presented case emphasizes the value of brush biopsy in the follow-up of oral squamous cell carcinoma, especially in examination of oral lesions covering a large area.
Authors: M L Nichols; F B Quinn; V J Schnadig; P Zaharopoulos; J A Hokanson; L Des Jardins; M M McCracken Journal: Arch Otolaryngol Head Neck Surg Date: 1991-12
Authors: F Chiesa; L Sala; L Costa; D Moglia; M Mauri; S Podrecca; S Andreola; R Marchesini; G Bandieramonte; C Bartoli Journal: Tumori Date: 1986-06-30