Literature DB >> 17902081

Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons.

Christof Gerlach1, Michael Smolinski, Holger Steuber, Christoph A Sotriffer, Andreas Heine, David G Hangauer, Gerhard Klebe.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17902081     DOI： 10.1002/anie.200701169

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  7 in total

Review 1.  Adding calorimetric data to decision making in lead discovery: a hot tip.

Authors:  John E Ladbury; Gerhard Klebe; Ernesto Freire
Journal:  Nat Rev Drug Discov       Date:  2009-12-04       Impact factor: 84.694

2.  A detailed thermodynamic profile of cyclopentyl and isopropyl derivatives binding to CK2 kinase.

Authors:  Takayoshi Kinoshita; Yusuke Sekiguchi; Harumi Fukada; Tetsuko Nakaniwa; Toshiji Tada; Shinya Nakamura; Kazuo Kitaura; Hiroaki Ohno; Yamato Suzuki; Akira Hirasawa; Isao Nakanishi; Gozoh Tsujimoto
Journal:  Mol Cell Biochem       Date:  2011-07-07       Impact factor: 3.396

3.  A comprehensive examination of the contributions to the binding entropy of protein-ligand complexes.

Authors:  Nidhi Singh; Arieh Warshel
Journal:  Proteins       Date:  2010-05-15

4.  Small-molecule inhibitors that target protein-protein interactions in the RAD51 family of recombinases.

Authors:  Duncan E Scott; Anthony G Coyne; Ashok Venkitaraman; Tom L Blundell; Chris Abell; Marko Hyvönen
Journal:  ChemMedChem       Date:  2014-12-02       Impact factor: 3.466

5.  Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions.

Authors:  David L Cramer; Bo Cheng; Jianhua Tian; John H Clements; Rachel M Wypych; Stephen F Martin
Journal:  Eur J Med Chem       Date:  2020-08-23       Impact factor: 6.514

6.  Prediction of sub-cavity binding preferences using an adaptive physicochemical structure representation.

Authors:  Izhar Wallach; Ryan H Lilien
Journal:  Bioinformatics       Date:  2009-06-15       Impact factor: 6.937

Review 7.  Limitations and lessons in the use of X-ray structural information in drug design.

Authors:  Andrew M Davis; Stephen A St-Gallay; Gerard J Kleywegt
Journal:  Drug Discov Today       Date:  2008-08-27       Impact factor: 7.851
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.