BACKGROUND AND PURPOSE: The purpose of this work was to test the feasibility of using high angular resolution diffusion imaging (HARDI)-based multitensor tractography to depict motor pathways in patients with brain tumors. MATERIALS AND METHODS: Ten patients (6 males and 4 females) with a mean age of 52 years (range, 9-77 years) were scanned using a 1.5T clinical MR unit. Single-shot echo-planar imaging was used for diffusion-weighted imaging (repetition time, 6000 ms; excitation time, 88 ms) with a diffusion-sensitizing gradient in 32 orientations and a b-value of 1000 s/mm(2). Data postprocessing was performed using both the conventional single- and multitensor methods. The depiction rate of the 5 major components of the motor pathways, that is, the lower extremity, trunk, hand, face, and tongue, was assessed. RESULTS: Motor fibers on both lesional and contralesional sides were successfully depicted by both the single-tensor and multitensor techniques. However, with the single-tensor model, the depiction of motor pathways was typically limited to the fibers of trunk areas. With the multitensor technique, at least 4 of 5 major fiber bundles arising from the primary motor cortex could be identified. CONCLUSION: HARDI-based multitensor tractography using a standard b-value (1000 s/mm(2)) can depict the fiber tracts from the face and tongue regions of the primary motor cortex.
BACKGROUND AND PURPOSE: The purpose of this work was to test the feasibility of using high angular resolution diffusion imaging (HARDI)-based multitensor tractography to depict motor pathways in patients with brain tumors. MATERIALS AND METHODS: Ten patients (6 males and 4 females) with a mean age of 52 years (range, 9-77 years) were scanned using a 1.5T clinical MR unit. Single-shot echo-planar imaging was used for diffusion-weighted imaging (repetition time, 6000 ms; excitation time, 88 ms) with a diffusion-sensitizing gradient in 32 orientations and a b-value of 1000 s/mm(2). Data postprocessing was performed using both the conventional single- and multitensor methods. The depiction rate of the 5 major components of the motor pathways, that is, the lower extremity, trunk, hand, face, and tongue, was assessed. RESULTS: Motor fibers on both lesional and contralesional sides were successfully depicted by both the single-tensor and multitensor techniques. However, with the single-tensor model, the depiction of motor pathways was typically limited to the fibers of trunk areas. With the multitensor technique, at least 4 of 5 major fiber bundles arising from the primary motor cortex could be identified. CONCLUSION: HARDI-based multitensor tractography using a standard b-value (1000 s/mm(2)) can depict the fiber tracts from the face and tongue regions of the primary motor cortex.
Authors: Van J Wedeen; Patric Hagmann; Wen-Yih Isaac Tseng; Timothy G Reese; Robert M Weisskoff Journal: Magn Reson Med Date: 2005-12 Impact factor: 4.668
Authors: Christopher Nimsky; Oliver Ganslandt; Dorit Merhof; A Gregory Sorensen; Rudolf Fahlbusch Journal: Neuroimage Date: 2005-12-20 Impact factor: 6.556
Authors: G Caiazzo; D Corbo; F Trojsi; G Piccirillo; M Cirillo; M R Monsurrò; F Esposito; Gioacchino Tedeschi Journal: J Neurol Date: 2013-10-15 Impact factor: 4.849
Authors: Alireza Radmanesh; Amir A Zamani; Stephen Whalen; Yanmei Tie; Ralph O Suarez; Alexandra J Golby Journal: Clin Neurol Neurosurg Date: 2014-12-08 Impact factor: 1.876
Authors: K Yamada; K Akazawa; S Yuen; M Goto; S Matsushima; A Takahata; M Nakagawa; K Mineura; T Nishimura Journal: AJNR Am J Neuroradiol Date: 2009-11-19 Impact factor: 3.825