Literature DB >> 17876289

Synthesis and biological evaluation of some novel Schiff's bases from 1,2,4-triazole.

Xiao-Xia Ye1, Zhen-Fei Chen, An-Jiang Zhang, Li-Xue Zhang.   

Abstract

We have synthesized a number of novel Schiff's bases from 4-amino-3-(D-glucoheptonic-hexitol-1-yl)-1H-1,2,4-triazole-5-thione. By attaching D-glucoheptonic-hexitol-1-yl residues to 1,2,4-triazole at the 3-position, the solubility of the title compounds has been improved greatly. All the products have been characterized by elemental analysis, IR, 1H-NMR, 13C-NMR and MS. The plant-growth regulating effects of the title compounds were examined. From the biological activity results, we found that most compounds showed weak to moderate activities.

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Year:  2007        PMID： 17876289      PMCID： PMC6157165          DOI： 10.3390/12061202

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  5 in total

1.  Studies on nitrophenylfuran derivatives part Xii. synthesis, characterization, antibacterial and antiviral activities of some nitrophenylfurfurylidene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

Authors:  B S Holla; P M Akberali; M K Shivananda
Journal:  Farmaco       Date:  2001-12

2.  Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.

Authors:  Marina Kritsanida; Anastasia Mouroutsou; Panagiotis Marakos; Nicole Pouli; Spyroula Papakonstantinou-Garoufalias; Christophe Pannecouque; Myriam Witvrouw; Erik De Clercq
Journal:  Farmaco       Date:  2002-03

3.  Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.

Authors:  B S Holla; B S Rao; K Shridhara; P M Akberali
Journal:  Farmaco       Date:  2000-05

4.  Synthesis and anthelmintic activity of 3,6-disubstituted-7H-s-triazolo(3,4-b)(1,3,4)thiadiazines.

Authors:  B A Nadkarni; V R Kamat; B G Khadse
Journal:  Arzneimittelforschung       Date:  2001

5.  Synthesis and studies on some new fluorine containing triazolothiadiazines as possible antibacterial, antifungal and anticancer agents.

Authors:  B Shivarama Holla; B Sooryanarayana Rao; B K Sarojini; P M Akberali; N Suchetha Kumari
Journal:  Eur J Med Chem       Date:  2006-04-17       Impact factor: 6.514
  5 in total

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