Literature DB >> 11505788

Synthesis and anthelmintic activity of 3,6-disubstituted-7H-s-triazolo(3,4-b)(1,3,4)thiadiazines.

B A Nadkarni1, V R Kamat, B G Khadse.   

Abstract

A series of 3,6-disubstituted-7H-s-triazolo(3,4-b)(1,3,4)thiadiazines was synthesized by the condensation of the appropriate 3-substituted-4-amino-5-mercapto (1,2,4) triazoles with substituted phenacyl bromides in alcoholic medium. These compounds have been studied for their in vivo anthelmintic activity in albino mice. A number of compounds showed promising activity when given by the oral route.

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Year:  2001        PMID: 11505788     DOI: 10.1055/s-0031-1300081

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  8 in total

1.  Synthesis and biological evaluation of some novel Schiff's bases from 1,2,4-triazole.

Authors:  Xiao-Xia Ye; Zhen-Fei Chen; An-Jiang Zhang; Li-Xue Zhang
Journal:  Molecules       Date:  2007-07-05       Impact factor: 4.411

2.  5-(4-Chloro-phen-yl)-3-(2,4-dimethyl-thiazol-5-yl)-1,2,4-triazolo[3,4-a]isoquinoline.

Authors:  F Nawaz Khan; P Manivel; K Prabakaran; Venkatesha R Hathwar; Mehmet Akkurt
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-04-10

3.  3-(4-Chloro-phen-yl)-5-phenyl-1,2,4-triazolo[3,4-a]isoquinoline.

Authors:  F Nawaz Khan; P Manivel; K Prabakaran; Venkatesha R Hathwar; Mehmet Akkurt
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-04-17

4.  5-Phenyl-3-(2-thien-yl)-1,2,4-triazolo[3,4-a]isoquinoline.

Authors:  F Nawaz Khan; P Manivel; K Prabakaran; Venkatesha R Hathwar; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-01-30

5.  Syntheses and biological activities of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines.

Authors:  Jian-yu Jin; Li-xue Zhang; Xian-xing Chen; An-jiang Zhang; Hai-le Zhang
Journal:  Molecules       Date:  2007-03-03       Impact factor: 4.411

6.  Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs.

Authors:  Jingde Wu; Xinyong Liu; Xianchao Cheng; Yuan Cao; Defeng Wang; Zhong Li; Wenfang Xu; Christophe Pannecouque; Myriam Witvrouw; Erik De Clercq
Journal:  Molecules       Date:  2007-08-22       Impact factor: 4.411

7.  Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole.

Authors:  Jian-yu Jin; Li-xue Zhang; An-jiang Zhang; Xin-Xiang Lei; Jiang-Hai Zhu
Journal:  Molecules       Date:  2007-07-27       Impact factor: 4.411

8.  3,5-Bis(4-methoxy-phen-yl)-1H-1,2,4-triazole monohydrate.

Authors:  Hai-Ying Wang; Jian-Ping Ma; Ru-Qi Huang; Yu-Bin Dong
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-05-14
  8 in total

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