Literature DB >> 10983278

Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.

B S Holla1, B S Rao, K Shridhara, P M Akberali.   

Abstract

A series of 3-substituted-4-[5-(2,4-dichlorophenyl)-2-furfurylidine]amino-5-me rcapto-1, 2,4-triazoles (3) are synthesised. Aminomethylation of 3 with formaldehyde and a primary/secondary amine furnished Mannich bases 4 and 5. Both Schiff bases 3 and Mannich bases 4 and 5 are characterised on the basis of IR, 1H NMR, mass spectral data and elemental analysis. All the newly synthesised compounds are tested for their antibacterial activities. Some of the selected compounds are also tested for their fungicidal and herbicidal properties.

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Year:  2000        PMID: 10983278     DOI: 10.1016/s0014-827x(00)00033-1

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  6 in total

1.  Synthesis and biological evaluation of some novel Schiff's bases from 1,2,4-triazole.

Authors:  Xiao-Xia Ye; Zhen-Fei Chen; An-Jiang Zhang; Li-Xue Zhang
Journal:  Molecules       Date:  2007-07-05       Impact factor: 4.411

2.  Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate.

Authors:  Hasan Tanak; Metin Yavuz
Journal:  J Mol Model       Date:  2009-07-03       Impact factor: 1.810

3.  Reaction of substituted furan-2-carboxaldehydes and furo[b]pyrrole type aldehydes with hippuric acid.

Authors:  Zita Puterová; Heinz Sterk; Alzbeta Krutosíková
Journal:  Molecules       Date:  2004-01-31       Impact factor: 4.411

4.  Reactions of substituted furan-2-carboxaldehydes and furo[b]pyrrole type aldehydes with benzothiazolium salts.

Authors:  Zita Puterová; Alzbeta Krutosíková; Antonín Lycka; Tatiana Durceková
Journal:  Molecules       Date:  2004-03-31       Impact factor: 4.411

5.  Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole.

Authors:  Jian-yu Jin; Li-xue Zhang; An-jiang Zhang; Xin-Xiang Lei; Jiang-Hai Zhu
Journal:  Molecules       Date:  2007-07-27       Impact factor: 4.411

6.  Synthesis and Antioxidant Activity of 2-Amino-5-methylthiazol Derivatives Containing 1,3,4-Oxadiazole-2-thiol Moiety.

Authors:  Kikkeri N Mohana; Chikkur B Pradeep Kumar
Journal:  ISRN Org Chem       Date:  2013-08-19
  6 in total

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