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Literature DB >> 17809404

Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" Suppressor.

Abstract

In a cell-free system, with RNA from a suppressible mutant of bacteriophage R17 as messenger,. no functional coat protein of the bacteriophage is synthesized unless serine-accepting soluble RNA from the suppressor strain, Escherichia coli S26RIE, is present.

Entities: Chemical Species

Year: 1965 PMID： 17809404 DOI： 10.1126/science.149.3682.417

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

56 in total

1. Isolation and characterization of lambda transducing bacteriophages for the su1+ (supD minus) amber suppressor of Escherichia coli.

Authors: D A Steege; B Low
Journal: J Bacteriol Date: 1975-04 Impact factor: 3.490

2. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR.

Authors: Christopher D Herring; Frederick R Blattner
Journal: J Bacteriol Date: 2004-10 Impact factor: 3.490

3. The initiation of viral protein synthesis in e. Coli extracts.

Authors: D Kolakofsky; T Nakamoto
Journal: Proc Natl Acad Sci U S A Date: 1966-12 Impact factor: 11.205

4. Role of guanosine 5'-triphosphate in the initiation of Peptide synthesis, I. Synthesis of formylmethionyl-puromycin.

Authors: J W Hershey; R E Thach
Journal: Proc Natl Acad Sci U S A Date: 1967-03 Impact factor: 11.205

5. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes.

Authors: M Salas; M B Hille; J A Last; A J Wahba; S Ochoa
Journal: Proc Natl Acad Sci U S A Date: 1967-02 Impact factor: 11.205

Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" Suppressor.

1. Isolation and characterization of lambda transducing bacteriophages for the su1+ (supD minus) amber suppressor of Escherichia coli.

2. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR.

3. The initiation of viral protein synthesis in e. Coli extracts.

4. Role of guanosine 5'-triphosphate in the initiation of Peptide synthesis, I. Synthesis of formylmethionyl-puromycin.

5. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes.

6. Suppressor-induced structural changes in a missense L-ribulokinase of Escherichia coli.

7. Polyamines enhance readthrough of the UGA termination codon in a mammalian messenger RNA.

8. Effect of mutation to streptomycin resistance on amber suppressor genes.

9. Recessive lethals: a new class of nonsense suppressors in Escherichia coli.

10. The effect of ribonuclease on polysomes and ribosomes of bacteria and animal cells.