Literature DB >> 17784801

Age-related deficits in component processes of working memory.

Adam Gazzaley1, Margaret A Sheridan, Jeffrey W Cooney, Mark D'Esposito.   

Abstract

Working memory deficits in normal aging have been well documented, and studies suggest that high memory load plus the presence of distraction negatively impacts successful memory performance to a greater degree in older individuals. However, characterization of the component processes that are impaired by these task manipulations is not clear. In this behavioral study, younger and older subjects were tested with a delayed-recognition and recall task in which the encoding and delay period were both manipulated. During the encoding period, the subjects were presented with either a single letter or multiple letters at their predetermined forward letter span, and the delay period was either uninterrupted or interrupted with a visual distraction. There was an age-related impairment of working memory recognition accuracy only in the combination of high memory load and distraction. These results suggest that when working memory maintenance systems are taxed, faulty recognition processes may underlie cognitive aging deficits in healthy older individuals. (PsycINFO Database Record (c) 2007 APA, all rights reserved).

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Year:  2007        PMID: 17784801     DOI: 10.1037/0894-4105.21.5.532

Source DB:  PubMed          Journal:  Neuropsychology        ISSN: 0894-4105            Impact factor:   3.295


  31 in total

1.  Age-Related Changes in 1/f Neural Electrophysiological Noise.

Authors:  Bradley Voytek; Mark A Kramer; John Case; Kyle Q Lepage; Zechari R Tempesta; Robert T Knight; Adam Gazzaley
Journal:  J Neurosci       Date:  2015-09-23       Impact factor: 6.167

2.  Age-related alterations in default mode network: impact on working memory performance.

Authors:  Fabio Sambataro; Vishnu P Murty; Joseph H Callicott; Hao-Yang Tan; Saumitra Das; Daniel R Weinberger; Venkata S Mattay
Journal:  Neurobiol Aging       Date:  2008-07-31       Impact factor: 4.673

3.  The response-signal method reveals age-related changes in object working memory.

Authors:  Arjun Kumar; Brian C Rakitin; Rohit Nambisan; Christian Habeck; Yaakov Stern
Journal:  Psychol Aging       Date:  2008-06

4.  Running enhances spatial pattern separation in mice.

Authors:  David J Creer; Carola Romberg; Lisa M Saksida; Henriette van Praag; Timothy J Bussey
Journal:  Proc Natl Acad Sci U S A       Date:  2010-01-19       Impact factor: 11.205

5.  Brain functional correlates of working memory: reduced load-modulated activation and deactivation in aging without hyperactivation or functional reorganization.

Authors:  Allison R Kaup; Sean P A Drummond; Lisa T Eyler
Journal:  J Int Neuropsychol Soc       Date:  2014-09-29       Impact factor: 2.892

6.  Distinct mechanisms for the impact of distraction and interruption on working memory in aging.

Authors:  Wesley C Clapp; Adam Gazzaley
Journal:  Neurobiol Aging       Date:  2010-02-09       Impact factor: 4.673

Review 7.  Language, executive function and social cognition in the diagnosis of frontotemporal dementia syndromes.

Authors:  Michał Harciarek; Stephanie Cosentino
Journal:  Int Rev Psychiatry       Date:  2013-04

8.  Reduced short-term memory span in aphasia and susceptibility to interference: contribution of material-specific maintenance deficits.

Authors:  Laura H F Barde; Myrna F Schwartz; Evangelia G Chrysikou; Sharon L Thompson-Schill
Journal:  Neuropsychologia       Date:  2009-11-17       Impact factor: 3.139

9.  The impact of age-related changes on working memory functional activity.

Authors:  Jason Steffener; Adam M Brickman; Brian C Rakitin; Yunglin Gazes; Yaakov Stern
Journal:  Brain Imaging Behav       Date:  2009       Impact factor: 3.978

10.  The effect of non-visual working memory load on top-down modulation of visual processing.

Authors:  Jesse Rissman; Adam Gazzaley; Mark D'Esposito
Journal:  Neuropsychologia       Date:  2009-02-04       Impact factor: 3.139

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